中文摘要：

抑郁症作为常见的情感障碍疾病,其发病率呈现逐年增加的趋势。研究显示慢性、低强度、长期的应激性生活事件是引发抑郁的主要原因,抑郁症患者及慢性应激抑郁模型动物边缘系统部分脑区尤其是海马部位,均存在神经可塑性改变,抑郁症发病的神经可塑性机制研究成为新亮点。近年来,中、西医学界对此进行了一些有益的探索,并取得了一定的进展。

英文摘要：

Depression is a common disease of emotional disorder; its incidence has an increasing tendency. Research showed that the main reason of depression was chronic, low intensity and long-term stressful life event. Neural plasticity exists in some partial brain areas of the limbic system especially in hippocampus of the depressed patients and model animals of depression induced by chronic stresses. Neural plasticity on depression is becoming the new highlight of the mechanism of depression. For the past few years, TCM medicine and western medicine have made a beneficial research and progress on it.