中文摘要：

目的;观察刺五加脑灵液联合舍曲林治疗肠易激综合征的临床疗效。方法：选取2008年6月～2012年6月间在本院治疗的89例肠易激综合征患者．随机分为对照组43例和观察组46例，对照组给予口服舍曲林，观察组给予舍曲林和刺五加脑灵液，疗程3月。于治疗前后使用汉密尔顿抑郁量表（HAMD）和焦虑量表（HAMA）进行神经心理学评分，并观察2组患者不良反应情况，疗程结束后统计疗效和单项症状（腹痛、腹泻、黏液便）有效率。结果：治疗前2纽患者HAMD、HAMA评分比较，差异无显著性意义（P〉0．05）；治疗后2组HAMD、HA／VIA评分均有下降，观察组HAMD评分与治疗前比较，差异有显著性意义（P〈0．05）；2组HAMA评分与治疗前比较，差异有显著性意义（P〈0．05），且观察组HAMA评分明显低于对照组，差异有显著性意义（P〈0．05），表明观察组患者焦虑和抑郁情绪改善更佳。治疗后2组腹痛改善有效率分别为93．5％和72．1％，差异有显著性意义（P〈0．05）；观察组腹泻改善有效率为80．4％，对照组为58．1％，观察组明显好于对照组，差异有显著性意义（P〈（1．05）；观察组黏液便改善率67．4％好于对照组51．2％，但差异无显著性意义（P〉0．05）。服药后2组均未出现严重不良反应。结论：剌五加脑灵液联合舍曲林治疗肠易激综合征患者疗效显著，对患者的焦虑和抑郁情绪有明显改善，不良反应较轻，值得临床推广使用。

英文摘要：

Objective. To investigate the therapeutic effect of Ciwu]ia Naoling oral liquid combined with sertraline for treatment of patients with irritable bowel syndrome. Methods： Eighty-nine irritable bowel syndrome patients admitted to our hospital from June of 2008 to June of 2012 were randomly divided into observation group（46 cases） and control group（43 cases）. The control group was given sertraline, and the observation group was given Ciwujia Nooling oral liquid combined with sertraline orally. The two groups were treated for 3 months. The scores of Hamilton rating scales for depression（HAMD） and Hamilton rating scales for anxiety（HAMA） as well as adverse reaction were observed before and after treatment. The effective rate for single symptom such as abdominal pain, diarrhea and mucous stool was compared between the two groups. Results= The differences of scores of HAMD and HAMA between the two groups were insignificant before treatment（P〉0.05）, and were significant after treatment （P 〈 0.05）, the improvement of the observation groups being superior to that of the control group（P〈0.05）. The differences of scores of HAMD and HAMA were significant in the observation group before and after treatment, while in the control group only the HAMA scores had significant difference before and after treatment（P 〈 0.05）. The effective rate for abdominal pain was 93.5%and that for diarrhea was 80,4% in the observation group, and was 72.1%, 58,1% in the control group respectively, the difference being significant（P〈0.05）. The effective rate for mucous stool was 67,4% in the observation group, which being insignificantly higher than 51.2% in the control group （P 〉0.05）. Adverse reactions of two groups were not serious. Conclusion： Ciwufia Naoling oral liquid combined with sertraline has good curative effect for patients with irritable bowel syndrome, and can relieve anxiety and depression significantly with less adverse reaction, being worth to be popularized.