中文摘要：

目的探讨呼气末二氧化碳分压（pressureofend—tidalcarbondioxideconcentration，PETCO2）的监测在阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者整夜多道睡眠图（PSG）监测中的应用及意义。方法对38例OSAHS患者行整夜同步PSG和PETCO2监测，将PETCO：波形耦合到PSG中，观察记录PETCO2波形特点和数值，并与PSG相关指标行相关性分析。结果睡眠期间呼吸平稳状态下PETCO2呈现梯形波，呼吸暂停时波形表现为一直线，低通气时呼气末平台的缩短或消失。非快动眼睡眠期、快动眼睡眠期以及整夜总睡眠时间的PETCO2平均值与呼吸暂停低通气指数及微觉醒指数呈负相关趋势（r值-0．458--0．688，P值均〈0．01），与最低及夜间平均动脉血氧饱和度呈正相关趋势（r值0．604—0．674，P值均〈0．01）。结论PETCO2的监测可应用于PSG，睡眠期间PETCO，的平均值在一定程度上能反映OSAHS患者呼吸紊乱的严重程度。

英文摘要：

Objective The purpose of this study was to investigate the end-tidal carbon dioxide concentration （PETCO2 ） monitoring coupling in polysomnography for patients with obstructive sleep apnea hypopnea syndrome （OSAHS） during sleep. Methods PETCO2 was sampled through an Oral-Nasal Cannula and measured using micro-stream eapnometer. Capnometer was calibrated according to the manufacturer instructions and integrated into the standard polysomnographic recordings. Thirty-eight consecutive patients underwent overnight polysomnography （PSG） were synchronously monitored PETCO2. All variables were recorded continuously and transferred to a computer for analysis. Results PETCO2 numeric values and waveform were displayed in real time on the PSG epoch. The mean PETCO2 of wake, non-rapid eye movement, rapid eye movement and total sleep time were negatively correlated with apnea- hypopnea index and arousal index （ r were - 0. 458 - - 0. 688, P 〈 0. 01 ） , were positively correlated with mean arterial oxygen saturation （ SaO2 ） and lowest SaO2 （ r were 0. 604 - 0. 674, P 〈 0. 01 ）. Conclusions The study provides preliminary data showing that PETCO2 potentially can be used in continuous monitoring of OSAHS patients. PETCO2 can indicate the severity of OSAHS.