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中文摘要：
上转换荧光纳米材料NaYF4：Yb，Er／Tm因具有独特的上转换发光性能，在固体激光器、三维立体演示和红外成像等很多方面都有着重要的应用。近年来，NaYF4：Yb，Er／Tm上转换纳米颗粒作为荧光标记物用于生物标记引起了研究者的浓厚兴趣。合成出高质量、高荧光性能的NaYF4：Yb，Er／Tm上转换纳米颗粒是使之能够在生物医学等领域广泛应用的前提条件。本文针对NaYF4：Yb，Er／Tm上转换荧光纳米颗粒的合成方法、表面修饰以及生物应用等方面的研究进展进行综述。
英文摘要：
Because of the unique up-converting optical property, up-conversion luminescent materials NaYF4：Yb, Er/Tm have a number of potential applications, including in solid-state lasers, three-dimensional displays, IR imaging, and many others. In resent years, up-converting NaYF4：Yb, Er/Tm nanoparticles have attracted considerable interests due to their potential use as fluorescent labels for sensitive biological detection. The synthesis of up-converting NaYF4 ：Yb, Er/Tm nanoparticles with high-quality and strong fluorescent performance is the precondition for their applications in biomedicine. In this paper, the studies on the synthesis, surface modification and biological applications of up-converting NaYF4 ： Yb, Er/Tm nanoparticles are summarized with 60 cited papers for providing a beneficial reference to researchers in their further work.
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