表面等离子体共振传感器具有灵敏度高、免标记及检测快速等优点,在生命科学、药物开发、公共安全、环境污染检测等领域具有广阔的应用前景。高灵敏度、小型化、集成化、低成本、高可靠性是未来表面等离子共振传感器发展的主要方向。介绍了棱镜耦合复合结构表面等离子体共振传感器在提高灵敏度和分辨率方面的研究新进展,重点论述了光纤表面等离子体共振传感器的研究现状和发展趋势,并对高通量、多组分识别表面等离子体成像技术以及金属微纳结构(颗粒)局域表面等离子共振传感技术的应用前景进行了讨论。
The use of surface plasmon resonance (SPR) sensors is increasingly popular in fundamental biological research, drug discovery, public security and environmental monitoring areas, due to their advantages of label-free, high sensitivity, real-time and rapid detection. The development of surface plasmon resonance sensors will focus on the greater sensitivity, miniaturization, integration, low cost and reliability in the future. The prism, coupling multi-layer composite configuration SPR sensors are introduced and emphasis is on the advance of fiber- coupled SPR sensors. Prospects of a high-throughput, multi-component identification surface plasmon resonance imaging technologies, as well as metal micro-nano structure (particles) localized surface plasmon resonance sensors are discussed.