中文摘要：

纤维化疾病是临床上常见的疾病,至今仍是一个治疗难题。近年来的研究发现,过氧化物酶体增殖物激活受体（PPARs）中PPAR-γ亚型的活化或激动剂在器官纤维化的发生过程中有调节作用,可减缓纤维化进程。本文就PPAR-γ与肝、肾、肺、心肌、眼及皮肤等器官纤维化发病关系的研究现状与进展做一综述。

英文摘要：

Fibrotic disease is a common clinical disease and the treatment is still a problem. Peroxisome proliferator activated receptor-γ（PPAR-γ） is a subtype of peroxisome proliferator-aetivated receptors（PPARs）. Recent studies have found that PPAR-γ＇s activators or agonists have a moderating effect in the occurrence of organ fibrosis, it may slow fibrotic process. In this article, we reviewed medical literatures related to PPAR-γ and fibrotic diseases in liver, kidney, lung, heart, eyes, skin and other organ.