中文摘要：

本试验旨在研究壳聚糖对断奶仔猪生长性能、粪便评分及血清激素和T淋巴细胞亚群的影响。选取28日龄断奶的杜×大×长三元杂交仔猪60头,随机分为5组（每组12头）：对照组饲喂基础饲粮,试验组分别饲喂在基础饲粮中添加250、500、1 000和2 000 mg/kg壳聚糖的试验饲粮。试验期14 d。结果表明：1）饲粮添加250~2 000 mg/kg壳聚糖显著提高断奶仔猪的平均日增重（ADG）（P〈0.05）,显著降低料重比（F/G）（P〈0.05）;2）饲粮添加250~2 000 mg/kg壳聚糖显著降低试验第11天断奶仔猪的粪便评分（P〈0.05）;3）饲粮添加适宜剂量的壳聚糖显著提高断奶仔猪的血清促生长激素释放激素（GHRH）（250~2 000 mg/kg）、生长激素（GH）（500~1 000 mg/kg）和瘦素（LP）（2 000 mg/kg）的浓度（P〈0.05）,显著降低血清促肾上腺皮质激素释放激素（CRH）（250~2 000 mg/kg）、促肾上腺皮质激素（ACTH）（500~1 000 mg/kg）、皮质醇（COR）（250~2 000 mg/kg）和可溶性CD8（sCD8）（500~2 000 mg/kg）的浓度（P〈0.05）。由此可见,饲粮中添加适宜剂量的壳聚糖能够促进断奶仔猪的生长,降低腹泻,缓解断奶应激。

英文摘要：

The effects of chitosan on growth performance, fecal score, serum hormones and T lymphocyte subset of weaned piglets were investigated in this study. A total of 60 weaned piglets （weaned at 28 days of age） were selected and randomly assigned to 5 groups, and each group contained 12 piglets. Piglets in control group were fed a basal diet, and those in experimental groups were fed the basal diet supplemented with 250, 500, 1 000 and 2 000 mg/kg chitosan, respectively. The experiment lasted for 14 days. The results showed as follows： 1） diet supplemented with 250 to 2 000 mg/kg chitosan significantly increased average daily gain （ADG） （P〈0.05）, and significantly decreased feed/gain （F/G） of weaned piglets （P〈0.05）. 2） Diet supplemented with 250 to 2 000 mg/kg chitosan significantly decreased fecal score on the day 11 of weaned piglets （P〈0.05）. 3） Diet supplemented with appropriate dose of chitosan significantly increased serum concentrations of growth hormone-releasing hormone （GHRH） （250 to 2 000 mg/kg）, growth hormone （GH） （500 to 1 000 mg/kg） and leptin （LP） （2 000 mg/kg） （P〈0.05）, and significantly decreased serum concentrations of corticotropin releasing hormone （CRH） （250 to 2 000 mg/kg）, adrenocorticotropic hormone （ACTH） （500 to 1 000 mg/kg）, cortisone （COR） （250 to 2 000 mg/kg）and soluble CD8 （sCD8）（500 to 2 000 mg/kg） of weaned piglets （P〈0.05）. The results suggest that diet supplemented with appropriate dose of chitosan can improve the growth, reduce the diarrhea and alleviate the weaning stress of weaned piglets.