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不同临床结局重症急性胰腺炎患者临床特点的对比研究
  • 时间:0
  • 分类:R657.51[医药卫生—临床医学;医药卫生—外科学]
  • 作者机构:[1]浙江省慈溪市人民医院消化内科,浙江慈溪315300, [2]第二军医大学长海医院消化内科,上海200433
  • 相关基金:国家自然科学基金(30801087)
中文摘要:

目的探究不同临床结局的重症急性胰腺炎的临床特点。方法对我院收治的63例重症急性胰腺炎患者的临床资料进行回顾性分析,根据临床结局,分为存活组与死亡组,对比两组患者的临床特点。结果存活组与死亡组患者的例数分别为53例(84.13%)与10例(15.87%),特发性重症急性胰腺炎患者的清创手术率与病死率均显著高于高脂血症患者与胆源性患者,差异具有统计学意义(均P〈0.05);死亡组急性生理与慢性健康(A.PACHE)II评分、CT严重指数(CTSI)、年龄、多脏器功能障碍/衰竭发生率以及局部并发症发生率均显著高于存活组,差异具有统计学意义(均P〈0.05)。结论重症急性胰腺炎患者的死亡与病因、年龄、多脏器功能障碍/衰竭、局部并发症等因素有关,值得进一步推广研究。

英文摘要:

Objective To investigate the clinical characteristics of different clinical outcome of patients with severe a- cute pancreatitis. Methods Clinical data of 63 cases of patients with severe acute pancreatitis in our hospital were ana- lyzed retrospectively.According to the clinical outcome, 63 cases were divided into survival group and death group,and clinical characteristics of two groups were compared. Results Cases of survival group and death group patients were 53 cases (84.13%) and 10 cases (15.87%) respectively. The incidence of debridement and mortality of idiopathic SAP was higher than those of biliary SAP and hyperlipidemic SAP (all P〈0.05).APACHE II score,CTSI, age, incidence of multi- ple organ dysfunction/failure and incidence of local complications in death group,were significantly higher than those of survival group,and the differences were statistically significant(all P〈0.05). Conclusion The death of patients with SAP is associated with age,disease cause,multiple organ dysfunction/failure and local complications,and the research is wor- thy of further promotion.

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