建立证候动物模型是探索西北燥证微观机制及其防治措施的关键。四诊是辨证的基本手段,虽"天然性差别"使对动物和对人的四诊及辨证方法截然不同,但二者却可统一于"宏观观察"。文章主张借助宏观观察手段,依据西北燥证主、兼分证辨证内容,以指标属性(直接性或间接性)分类为基础,筛选适用于造模动物中医西北燥证辨证的宏观观察指标,搭建造模动物宏观观测指标与人体西北燥证主兼分证症状表现间的对应关系,进而建立SD大鼠中医西北燥证指标结构辨证方案;运用指标量化方案,以等级变量描述SD大鼠各辨证指标及其结构,参照大鼠中医西北燥证指标结构辨证方案,应用对比分析法实现SD大鼠西北燥证主兼分证的辨识,并藉此评价西北燥证动物模型。
Establishing syndrome-model is the key process of northwest dryness syndrome research, which related to microcosmic pathogenesis and preventive methods. As we know, four diagnostic methods is the main way of syndrome differentiation. Although the TCM diagnostic methods are more different between human and animal, those have the same characteristic of using the macrographs. The article proposes that choose the applicative macroscopic indexes of syndrome differentiation basing on the human northwest dryness syndrome identification of main-syndrome and subordinate-syndrome, as well as classification of macroscopical indexes according to the existence of direct relativity. Furthermore, we can build and apply 'index-structure-symptoms-differentiation-program'. Describing index-structure-details by ranked dates which quantify by quantitative analysis program, so we can carry on animal syndrome differentiation and evaluate the new syndrome-model by using the comparative analysis approach referring to 'index-structure-symptoms-differentiation-program'.