目的:研究分析无痛可视人工流产术全麻药物对生命指征的影响以及安全保障的最佳用药量。方法:选择五组(瑞芬太尼、瑞芬太尼+丙泊酚、瑞芬太尼+咪唑安定、丙泊酚、丙泊酚+芬太尼)常用的麻醉药。用于无痛可视人工流产术。将受术者随机分为五组,每组60例患者。观察T、R、HR、BP、SpO2等变化情况,计算平均值及标准差并进行组间对比分析。观察各组麻醉用药,探索最佳用药量。结果:五组麻醉药在无痛可视人工流产术中的应用对生命指征的影响以瑞芬太尼+丙泊酚组最小,经统计学分析,P〈0.05。安全保障的最佳用药量分别为瑞芬太尼0.9~1.4μg/kg、丙泊酚1.9~2.2mg/kg。结论:无痛可视人工流产术全麻药物以“瑞芬太尼+丙泊酚”组最佳。剂量分别为0.9~1.4tLg/kg、1.9~2.2mg/kg,对生命指征的影响最小,安全系数最高。
Objective: To observe the anesthesia drugs on the impact of life as well as indications of the best security dosage in painless visual induced abortion. Methods: Selected five groups (remifentanil, remifentanil+propofol, remifentanil+midazolam, propofol, fentanyl+propofol) anesthetic commonly used for painless visual flow operation.The patients were randomly divided into five groups, each group included 60 cases.Observation of T, R, HR, BP, SpO2 and other changes in the mean and standard deviation calculated for comparison between groups.To observe the group of narcotic drugs, and explore the best dosage. Results: In five groups of anesthetic in painless artificial abortion visualization applications, the impact of remifentanil + propofol group was the smallest, P〈0.05.In security the best dosage were remifentanil 0.9-1.4 μg/kg, propofol 1.9-2.2 mg/kg. Conclusion:The best drugs of painless visual anesthesia is remifentanil + propofol.The dose were 0.9-1.4 μg/kg, 1.9-2.2 mg/kg respectively.Indications of the impact of the lives of the smallest, the highest safety factor.