目的:观察失荅剌知丸治疗腔隙性脑梗死患者认知功能障碍的临床疗效。方法:将80例腔隙性脑梗死患者随机分为对照组及治疗组各40例,两组患者合并有高血压、糖尿病、高血脂者予对症治疗。对照组静滴血栓通注射液500mg,每日1次,治疗14天;治疗组静滴血栓通注射液,同时口服失荅剌知丸,1日2次,10g/次,治疗14天;对两组患者治疗前和治疗后进行蒙特利尔认知评估量表(Mo CA)评分。结果:治疗前两组Mo CA评分两组差异无统计学意义(P﹥0.05);治疗后治疗组Mo CA评分差异有统计学意义(P﹤0.05);对照组治疗前后无显著差异(P﹥0.05)。结论:回药方失荅剌知丸对腔隙性脑梗死患者认知功能障碍有明显改善作用。
objective To investigate The curative effect observation of Shi da la zhi wan treatment on ischemic stroke of cognitive disorder. Methods 80 cases ischemic stroke were randomly divided into the control group and the treatment group,40 cases in each group. Two groups of patients with high blood pressure,diabetes,hyperlipidemia to symptomatic treatment. tthe control group were treatment with Xue Shuan Tong injection 500 mg,once per day for14 days; the treatment group were given Xue Shuan Tong injection and Shi da la zhi wan,10 g / time,twice per day for14 days. Cognitive function and the amelioration of intelligence were assessed before and after treatment. Results The montreal cognitive assessmentof score both groups before treatment had no significant difference( P 〉0. 05).Treatment group after treatment of Mo CA score difference was statistically significant( P ﹤ 0. 05); The control group before and after treatment had no significant difference( P ﹥ 0. 05). Conclusion The Shi da la zhi wan can improve the cognition of the patients with cognitive impairment after cerebral infarction.