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Handheld optical coherence tomography device for photodynamic therapy
  • ISSN号:0023-074X
  • 期刊名称:《科学通报》
  • 时间:0
  • 分类:TP334[自动化与计算机技术—计算机系统结构;自动化与计算机技术—计算机科学与技术] TQ463[化学工程—制药化工]
  • 作者机构:[1]State Key Laboratory of Low-dimensional Quantum Physics and Laboratory of Atomic and Molecular Nanosciences, Department of Physics, Tsinghua University, Beijing 100084, China, [2]Department of Laser Medicine, Chinese PLA General Hospital, Beijing 100853, China, [3]School of Electronic Engineering, Tianjin University of Technology and Education, Tianjin 300222, China
  • 相关基金:The authors' would like to thank the New Raysing CompanyJbr their technical support. This work was supported in part by the National High-Tech Research and Development Program of China (2006AAO2Z472), National Bas& Research Program of China (001CB510307 and 2009CB929400), National Natural Science Foundation of China (90508001, 10676014 and 10574081) and Tsinghua University Initiative Scientific" Research Program.
中文摘要:

光力学的治疗(太平洋夏季时间) 是为港口酒污点(PWS ) 的一个很有效的处理。指导并且估计太平洋夏季时间治疗,手持光连贯断层摄影术(10 月) 探查为 PWS 病人的即时成像被设计。系统与 1310 nm, 90 nm 的 3 dB 带宽和 9 mW 的光力量的中心波长使用轻来源。系统也有 8 m 的一个空间决定(侧面) 慲獮敦瑣潩 ? 晥楦楣湥祣?? 慣楴湯捩挠楨潴慳? 敤楲慶楴敶 ???? 琭楲敭桴汹挠楨潴慳? 档潬楲敤 ???? 慷 ? 浥汰祯摥愠 ? 桴 ? 敶瑣牯讈吗??

英文摘要:

Photodynamic therapy (PDT) is a very effective treatment for port wine stains (PWS). To guide and assess PDT treatment, a handheld optical coherence tomography (OCT) probe was designed for real-time imaging of the PWS patient. The system uses a light source with a center wavelength of 1310 nm, -3 dB bandwidth of 90 nm and an optical power of 9 mW. The system also has a spatial resolution of 8 μm (lateral)× 7μm (axial), an imaging rate of 4 frames per second, and a 102 dB sensitivity. We then demonstrate that the OCT imaging system can clearly distinguish between normal and PWS tissues. Therefore, the system can provide valuable guidance for PDT treatment.

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期刊信息
  • 《科学通报》
  • 北大核心期刊(2011版)
  • 主管单位:中国科学院
  • 主办单位:中国科学院
  • 主编:周光召
  • 地址:北京东黄城根北街16号
  • 邮编:100717
  • 邮箱:csb@scichina.org
  • 电话:010-64036120 64012686
  • 国际标准刊号:ISSN:0023-074X
  • 国内统一刊号:ISSN:11-1784/N
  • 邮发代号:80-213
  • 获奖情况:
  • 首届国家期刊奖,中国期刊方阵“双高”期刊,第三届中国出版政府奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),美国数学评论(网络版),美国工程索引,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:81792