微小RNA(micro RNA,mi RNA)是一种在进化上高度保守的内源性非编码单链小RNA。近年来研究表明,mi RNA在肿瘤发生发展、脂肪代谢、血管生成等方面扮演着重要的角色,其通过靶基因在一定程度上调控细胞的生长、发育和增殖,并且与多种疾病有着密切的联系。现从以上3个方面对mi R-27的最新研究进展进行简要综述,以期为mi R-27的后续研究提供理论依据,丰富mi RNA的研究内涵。
Micro RNA(mi RNA) is a highly conserved endogenous non-coding single stranded small RNA in evolution. Recent studies show that mi RNA plays an important role in the development of tumor, angiogenesis, and energy metabolism, mi RNA regulates cell growth, development and proliferation through targeting gene, and closely associates with many diseases. The objective of this review is to summarize the recent research progresses of mi R-27 to improve the way for the further studies.