目的:探讨使用椎管内麻醉进行分娩镇痛对新生儿的远期影响。方法:2004年11月~2005年12月在保定市第一中心医院足月阴道分娩的儿童共640例,选择分娩镇痛组105例和非镇痛分娩组116例,对其进行适应行为评定及韦氏智力测验,调查所得结果进行分析比较。所有数据采用Excel软件进行录入,应用SPSS17.0软件包进行统计分析,计数资料采用χ^2检验,计量资料采用t检验。结果:两组儿童适应行为量表评定及韦氏智力测验结果比较差异均无统计学意义(P〉0.05)。结论:分娩镇痛对新生儿远期社会适应能力和智力无明显影响,椎管内麻醉用于分娩镇痛是安全的,可以广泛应用于临床。
Objective: To explore the long - term effect of labor analgesia with intraspinal anesthesia on neonates. Methods: A total of 640 full - term children born after vaginal delivery were selected from the hospital from November 2004 to December 2005, then 105 children (labor analgesia group) and 116 children (non -labor analgesia group) were selected. Adaptive behavior assessment and Wechsler intelligence test were performed, and then the results were analyzed and compared. All the data were typed into Excel software, SPSS 17.0 soft ware was used for statistical analysis ; the enumeration data were analyzed byx2 test, while the measurement data were analyzed by t test. Results : There was no statistically significant difference in the results of adaptive behavior assessment and Wechsler intelligence test between labor analgesia group and non - labor analgesia group ( P 〉 0. 05 ) . Conclusion: Labor analgesia has no obvious impact on long - term social adaptation ability and intelligence of neonates, intraspinal anesthesia is safe for labor analgesia, which can be widely used in clinical trials.