中文摘要：

蛋白质－能量消耗在慢性肾脏病中发病率较高，其发病机制复杂，是不良预后和高死亡率的独立危险因素之一。一旦发病，治疗效果欠佳，因此早期发现、诊断和治疗非常重要。目前蛋白质一能量消耗诊断依据国际肾脏营养与代谢学会提出的标准，包括生化指标、非预期的身体质量降低、肌肉量丢失、饮食蛋白质和，或热量摄人不足4个方面。针对蛋白质－能量消耗采取的首选治疗方法为适当补充营养物质，保证足够热量和蛋白质的摄入，其他药物治疗的效果尚待证实。本文对国内外慢性肾脏病蛋白质－能量营养不良诊疗领域的研究进展进行综述，旨在拓展医生对本病的认识，造福患者。

英文摘要：

Protein Energy wasting in chronic renal disease has a higher prevalence, it has complex pathogenesis, and becomes an independent risk factor of poor prognosis and high mortality. And in the event of ineffective in treatment, so early detection, diagnosis and treatment is very important. The current diagnostic criteria for protein and energy wasting based on International Society of Renal Nutrition and Metabolism rose, including biochemical parameters, unin- tended lower body mass, muscle mass loss, dietary protein and/or calorie intake four aspects. The preferred treatment method for protein energy wasting taken to be appropriate to add nutrients to ensure adequate intake of calories and protein, the effect is yet to be confirmed by other medications. Combined domestic and foreign idea which protein to chronic kidney disease-progress in the field of energy malnutrition clinic are reviewed to expand physician awareness of the disease, benefit to patients.