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Efficient Synthesis of the Functionalized Spiro[indoline-3,4＇-pyridine] via Four-component Reaction
  • ISSN号：1001-604X
  • 期刊名称：《中国化学：英文版》
  • 分类：O623.624[理学—有机化学;理学—化学] TQ252.4[化学工程—有机化工]
  • 作者机构：[1]College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China
  • 相关基金：Supporting information for this article is available on the WWW under http：//dx.doi.org/10.1002/cjoc.201100657 or from the author.Acknowledgements This work was supported by the National Natural Science Foundation of China （No. 21172189）.
作者： 孙晶[1], 吴群[1], 张藜娟[1], 颜朝国[1]
关键词： 反应条件, 高效合成, 官能化, 四组分, 吲哚, 二氢, 吡啶, 螺, spiro compound, isatin, multicomponent reaction, electron-deficient alkyne, 1,4-dihydropyridine
中文摘要：

为 functionalized spiro 的一个有效合成过程[indoline-3,4-pyridine ] 作为基础催化剂与 triethylamine 经由 arylamines， acetylenedicarboxylates，靛红和 malononitrile 的四部件的反应被开发。这反应的优点正在使用普通开始的材料，温和反应条件，反应物的宽广范围和运作的简洁。

英文摘要：

An efficient synthetic procedure for the functionalized spiro[indoline-3,4＇-pyridine] was developed via the four-component reactions of arylamines, acetylenedicarboxylates, isatins and malononitrile with triethylamine as the base catalyst. The advantages of this reaction are using common starting material, mild reaction conditions, broad scope of reactants and operational simplicity.

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期刊信息
  • 《中国化学：英文版》
  • 主管单位:
  • 主办单位:中国化学会
  • 主编：
  • 地址：上海市枫林路354号中科院上海有机化学研究所
  • 邮编：200032
  • 邮箱：
  • 电话：021-54925243
  • 国际标准刊号：ISSN：1001-604X
  • 国内统一刊号：ISSN：31-1547/O6
  • 邮发代号:4-646
  • 获奖情况:
  • 中国期刊方阵“双高”期刊
  • 国内外数据库收录:
  • 美国化学文摘（网络版）,荷兰文摘与引文数据库,美国科学引文索引（扩展库）,日本日本科学技术振兴机构数据库,英国英国皇家化学学会文摘
  • 被引量:175