目的:探讨代谢综合征的中医病理特点和证候兼杂规律。方法:收集491例代谢综合征患者的临床资料,采用证素辨证方法,分析中医病位和病性,探讨证候兼杂特点。结果:病位证素:主要在脾、肾和肝,分别占60.4%、58.2%和51.5%;病性证素:实证证素中痰、湿和瘀分别为77.1%、65.9%和61.3%;虚证证素阴虚、气虚分别为64.7%和60.0%;证的兼杂:各证型均存在不同程度的脾、痰、湿和瘀病理证素的兼杂。结论:代谢综合征患者的病位主要在脾、肾和肝;病性属虚实夹杂;痰、湿、瘀贯穿疾病始终。
Objective: To characterize the TCM pathologic features of MS, and to identify the miscellaneous and progressive patterns of MS. Methods : Data from 491 MS patients was analyzed to identify the main niduses, features and nature of MS, with syndrome element differentiation method, and the patterns of miscellaneous and progressive tendency of MS. Results : The niduses of MS were located in spleen, kidney, liver, heart and lung, mainly in the spleen ( 60.4% ), kidney ( 58.9% )and liver ( 51.5% ). The sthenia-syndrome was consisted of phlegm, damp, blood stasis, hot and qi stagnation, with phlegm, damp and blood stasis at a higher proportion of 77.1%, 65.9% and 61.3% respectively. The mixed features of the syndrome: The mixing degree of the niduses and the nature in each syndrome type was different, spleen, damp and blood stasis were mixed in all niduses. Conclusions: MS niduses are mainly located at spleen, kidney and liver. The feature of MS is intermingled deficiency and excess, with phlegm, damp and blood stasis presented throughout the course of the disease.