中文摘要：

线粒体是卵子的质量标志，其数量和功能异常导致卵细胞及胚胎质量低下。卵母细胞线粒体移植技术有望成为改善卵母细胞及胚胎质量和提高辅助生殖成功率新的治疗手段。本文就线粒体在卵母细胞成熟及着床前胚胎发育中的作用及线粒体移植疗法的最新研究进展进行了综述。

英文摘要：

Mitochondrion is a critical indicator of oocyte quality. The abnormality in mitochondrial quantity and function always leads to low quality of oocytes or embryos in assisted reproduction. The oocyte mitochondria transplantation has become a new method for improving the oocyte/embryo quality and increasing the success rate in assisted reproduction treatment. In this review, we explain the roles that mitochondria play in oocyte maturation and embryo development during preimplantation, and highlight the future application of mitochondria transplantation therapy in assisted reproduction treatment.