中文摘要：

我们发现过氧化氢酶在三孢布拉氏霉菌抵抗氧胁迫（H2O2）中具有一定的保护作用，从而引发菌体合成大量β-胡萝卜素和番茄红素。当发酵培养24h时加入20μmol／L的H2O2，产生的β-胡萝卜素比对照提高了59．4％；当培养36h时加入75μmol／L的H2O2，产生的番茄红素比对照提高了77．7％；在菌体积累这两种类胡萝卜素的同时，过氧化氢酶的活性显著降低，说明过氧化氢酶因猝灭H2O2而大量消耗，同时引发菌体合成较多的β-胡萝卜素和番茄红素，以猝灭氧自由基对机体造成的损伤。这一现象说明在氧胁迫条件下，过氧化氯酶作为信号因子激发菌体合成类胡萝卜素，从而保护菌体正常生长和代谢。

英文摘要：

We found that catalase protected Blakeslea trispora form attacking of oxygen stress （hydrogen peroxide）. Consequently, the microhe was stimulated and synthesized a great deal of β-carotene and lycopene. The yield of β-carotene produced by adding H2O5 （20 μmol/l） to the 24-hour old cultures of B. trispora reached 521mg/1 and resulted L in 59.4% higher than that without addition; besides, the yield of lycopene produced by adding H2O2 （75 μmol/l） to the 36-hour old cultures of B. trispora reached 350mg/l and resulted in 77.7% higher than that without addition; at the same time, the activity of catalase reduced obviously. The phenomena indicated catalase was consumed for catalysing H2O2 remarkably. Simultaneously B. trispora was triggered and the cells accumulated a large number of these two carotenoids to avoid damage of oxygen stress. These results suggested that as a singnal catalase triggered B. trispora to synthesize a lot of β -carotene and lycopene and protect the microbe.