中文摘要：

γδT细胞是一群不同于αβT细胞的T淋巴细胞群,其表面T细胞受体由γ链和δ链组成。而γδT细胞本身亦是一群高度异质性细胞,其亚类种类多、表型多变、功能丰富。γδT细胞除传统的Vδ1、Vδ2和Vδ3γδT细胞外,还可根据其功能差异分为调节性γδ、产生IL-17的γδ、产生干扰素的γδT细胞、人类错配修复基因2特异性γδT细胞以及白细胞介素6γδT细胞。γδT细胞各亚类间生物学特性各异,在机体肿瘤、感染及自身免疫性疾病等的发生、发展中均有重要作用,被认为是机体连接天然免疫与适应性免疫功能的桥梁。

英文摘要：

γδT cells are special T cells that different from αβ T cells, the surface T cell reporter of which consists of γ chain and δ chain. γδT cells are also a group of highly heterogeneous cells,with multiple subsets, variable phenotypes and rich function. In addition to the traditional Vδ1, δ2 and VK33,γδT cells, γδT cells can also be classified into γδTreg,Tγδ17 ,hMSH2 specificity γδT cells and IL-6 ＋ γδT cells according to their functional differences. γδT cells are considered to be the bridge in innate and adaptive immune function and are different in biological characteristics, which has an important role in the development of autoimmune diseases, cancer and infection.