中文摘要：

目的：观察阿魏酸的体外神经保护活性。方法：体外培养PC12细胞,建立缺氧损伤,兴奋性氨基酸损伤,自由基损伤三种损伤模型,采用噻唑蓝（MTT）法观察阿魏酸对PC12细胞存活力的影响。结果：与各模型组比较,阿魏酸在1～100μmol/L浓度范围内可显著升高PC12细胞D（λ）570值（P〈0.05或P〈0.01）。结论：阿魏酸对PC12细胞缺氧损伤、兴奋性氨基酸损伤、自由基损伤均有不同程度的保护作用。

英文摘要：

Objective：To investigate the neuroprotective effect of ferulic acid on PC12 cells injuries.Methods：With three models of PC12 cells injured by hypoxia,excitatory amino acids（EAA） and radical,the effect of ferulic acid on injured PC12 cells was observed by MTT assay.Results：Compared with three models,ferulic acid（1～100 μmol/L） could promote cell viability notably（P0.05 or P0.01）.Conclusion：Ferulic acid has notable protective effect on PC12 cells injured by hypoxia,EAA and radical.