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苯并咪唑类没食子酸酯抗菌化合物的性质及应用
  • ISSN号:1004-7964
  • 期刊名称:《皮革科学与工程》
  • 时间:0
  • 分类:TS529.1[轻工技术与工程—皮革化学与工程]
  • 作者机构:[1]四川大学皮革化学与工程教育部重点实验室,四川成都610065, [2]四川大学制革清洁技术国家工程实验室,四川成都610065
  • 相关基金:国家自然科学基金(21106088); 高等学校博士学科点专项科研基金(20110181120079)
中文摘要:

苯并咪唑类没食子酸酯(BG)是本实验室合成的、新的抗菌化合物。本文选择了其中已经XRD确定了结构的1-没食子酸乙酯-2-(对溴)苯氧甲基苯并咪唑(BG-Br)为代表进行研究。用BG-Br乳液和BG-Br二甲亚砜溶液分别处理蓝湿皮,采用抑菌圈法和振荡法测定处理皮样的抗菌效果;将BG-Br乳液和BG-Br溶液分别与皮粉作用,对处理皮粉进行DSC分析;观察BG-Br在明胶凝胶中的渗透情况。结果表明,BG-Br的最小抑菌浓度范围为8×10-5~4×10-4g/m L,处理的皮革有较好的抗菌效果;在明胶中的渗透性较好,但处理的铬皮粉的热稳定性会有所下降。总之,这种新的材料有可能在皮革工业上应用,以制备具有一定抗菌性能的皮革。

英文摘要:

Benzimidazole gallate (BG) is a new series of antibacterial compounds synthesized in our laboratory. The 1- gallate-2-(p-bromo) phenoxy methyl benzimidazole (BG-Br),whose structure had been identified by XRD, was chosen as a representative research. The wet blues 'were treated with both BG-Br emulsion and BG-Br in DMSO solution and the treated leathers were evaluate the antibacteria effect with the bacteriostatic circle method and oscillation method. Then, the chromed hide powder was treated with BG-Br emulsion and BG-Br in DMSO solution and the thermol properties of the treated powder was studied with DSC.Also the penetration of the both kind of BG-Br in the gelatin gel was measured. The results showed that the minimum inhibitory concentration range of BG-Br was 8×10-5 g/mL to 4×10-4 g/mL and the leather treated with BG-Br has a good antibacterial effect; Both kind of the BG-Br could well penetrate in gelatin gel, however, the thermal stability of chromed hide powder treated with BG-Br was lower than the control. In conclosion, this new material might be used in tanning industry for an antibacterial leather.

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期刊信息
  • 《皮革科学与工程》
  • 北大核心期刊(2011版)
  • 主管单位:教育部
  • 主办单位:中国皮革工业协会 四川大学
  • 主编:单志华
  • 地址:成都市一环路南一段24号四川大学皮革工程系
  • 邮编:610065
  • 邮箱:chenling00@263.net
  • 电话:028-85460597
  • 国际标准刊号:ISSN:1004-7964
  • 国内统一刊号:ISSN:51-1397/TS
  • 邮发代号:62-185
  • 获奖情况:
  • 中国学术期刊综合评价数据库来源期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),中国中国科技核心期刊,中国北大核心期刊(2008版),中国北大核心期刊(2011版)
  • 被引量:3586