采用超高效液相色谱质谱联用法,ESI离子源正离子模式选择离子扫描模式对护肝片中五味子醇甲和五味子醇乙进行定量分析。五味子醇甲和五味子醇乙在一定范围内线性良好,相关系数均大于0.999,加样回收率为98.41%和96.91%(n=6)。该方法快速、灵敏度高、选择性好,适合测定护肝片中五味子醇甲和五味子醇乙的定量分析。
Schisandrin and Schisandrol B were determined by UPLC - ESI - Q - TOF - MS. The linear relation- ship between the concentration and peak areas of the Sehisandrin and Sehisandrol B were all linear(r 〉0. 999). The average recoveries ( n = 6) were 98.41% and 96.91%. The method was rapid, sensitive, selective and suitable for the quantitative analysis of Schisandrin and Sehisandrol B in Hugan Pian.