从岭南地区习用药毛冬青Ilex pubescens Hook.Et.Am.根的乙酸乙酯提取物中分离得到2个化合物,经理化鉴定及波谱技术分析,并结合文献对照,鉴定为乌苏烷型三萜——毛冬青皂苷元A(ilexgenin A,1)和乌苏烷型三萜皂苷——毛冬青皂苷A1(ilexsaponin A1,2)。首次利用2DNMR(^1H-^1H COSY,HMBC和HMQC)技术对此两个化合物的^1H和^13CNMR数据进行了全归属。
Two known compounds ilexgenin A (1) and ilexsaponin A1 (2), were isolated from the root of llex pubescens, which is a traditional Chinese medicine used for the treatment of cardiovascular diseases. These two compounds were elucidated by chemical method,physical method and spectroscopic analysis methods. The signals of ^1H and ^13C NMR spectra of compounds 1 and 2 were recorded and completely assigned by 2D NMR experiments,including ^1H-^1H COSY, HM-BC and HMQC.