中文摘要：

目的研究远程氩等离子体对医用聚四氟乙烯（PTFE）表面的灭菌及改性。方法通过载体定量灭菌实验测定远程氩等离子体对PTFE表面大肠杆菌的杀灭效果,并利用接触角测量、质量损失率计算和X射线光电子能谱分析（XPS）研究灭菌前后PTFE表面结构、性能的变化。结果在放电功率100 W,放电时间120 s,氩气流量20 cm3/min的条件下,远程及常规氩等离子体均可有效灭活大肠杆菌（GE≥3.769）;但经远程氩等离子体灭菌后,PTFE表面的亲水性（水接触角为58.5°）明显优于常规氩等离子体灭菌后的PTFE表面（水接触角为70.5°）,同时受损及降解程度低（表面质量损失率仅为11.8%）。远程氩等离子体可以在一定程度上抑制电子、离子的刻蚀作用,强化自由基反应,对PTFE表面的脱氟作用更强,从而引入更多的含氧基团。结论远程氩等离子体在有效杀灭大肠杆菌的同时,可使PTFE表面获得更好的改性效果。

英文摘要：

Objective To investigate the surface sterilization and modification of medical poly （tetrafluoroethylene） （PTFE） by remote argon plasma. Methods Carrier quantitative bactericidal test was used to examine the germicidal effect （GE） of the E. coil on the surface of medical PTFE film and surface structure, performances of sterilized PTFE were characterized by the water contact angle, mass loss and X-ray photoelectron spectroscopy （XPS）. Results Both remote and conventional argon plasmas could sterilize effectively（GE≥3. 769） in the conditions of plasma RF power 100 W, exposure time 120 s and argon flux 20 cm^3/min. Remote argon plasma sterilization made the PTFE surface have higher hydrophilicity （ θ = 58.5°） than the conventional argon plasma sterilization （ θ = 70.5°） and did not cause remarkable degradation and damages in terms of the mass loss （mass loss was 11.8%）. Remote argon plasma sterilization could enhance interaction reactions with argon radicals relative to those with electron and argon ions, thereby contributing more effectively to defluorination （F/C= 2.24） from the PTFE than the conventional argon plasma sterilization （F/C = 2. 49） and more effectively to the formation of oxygen functionalities on the PTFE surface. Conclusion Remote argon plasma can inactivate E. coli effectively and at the same time bring better surface modification of PTFE.