中文摘要：

目的：探讨血清CA125测定对评估卵巢高级别浆液性腺癌术后血CA125下降情况与残余病灶大小关系的价值。方法：回顾性研究卵巢高级别浆液性腺癌IIc-IV期患者62例,按照瘤体减灭术后残余病灶大小分为3组,A组为术后残余病灶〉1cm,B组为≤1cm者,C组为肉眼未见病灶者,查阅术前、术后第1次化疗后血CA125值。结果：C组下降百分比与B组、A组相比有统计学差异（分别为P=0.024,P=0.002）。结论：术后残余病灶大小不同的患者血CA125下降情况不同,在关于肿瘤标志物的研究中将肉眼未见病灶组单独列出研究有很大的必要性。

英文摘要：

Objective： To investigate the value of serum CA125 in assessment of the relationship of high grade ovarian serous adenocarcinoma postoperative CA125 decrease and the residual lesion size.Methods： A retrospective study of 62 cases of high grade serous ovarian adenocarcinoma with stage IIc-IV was arranged.Three groups were divided in accordance with the tumor cytoreductive postoperative residual lesion size,group A for postoperative residual lesions 1cm,group B for ≤ 1cm,group C lesions were no gross residual disease.Serum CA125 values preoperatively and after first chemotherapy postoperatively were detected.Results： Compared with group A and B,the decreased percentage of group C had a statistically significant difference（P=0.024 and P=0.002,respectively）.Conclusions： The extents of CA125 decline with different postoperative residual lesion size were distinctive.It was necessary to separate the no gross residual disease group from others.