目的:从文献计量学角度对产肺炎克雷伯菌碳青霉烯酶( KPC)肺炎克雷伯菌相关文献进行分析以便跟踪产KPC肺炎克雷伯菌研究进展。方法检索至今的Pubmed、Embase、ISI数据库中(时间:1970-01-2013-08)产KPC肺炎克雷伯菌相关文献,对纳入研究文献的发表年限、作者、语种、文章类型、流行病学、分子耐药机制和治疗等进行分析。结果纳入研究的文献共257篇(第1篇于2001年报道),综述10篇,会议文章4篇,论著233篇,其他16篇。发表量逐年增高,美国报道最多,中国报道居第3位。结论产KPC肺炎克雷伯菌已经引起了世界范围内的广泛关注,对其研究内容愈加深入。
Objective To analyze the literature on carbapenemases -pro-ducing Klebsiella pneumoniae (KPC) in the world and to follow the research progress of KPC.Methods All publications about KPC -producing Kleb-siella pneumoniae were searched on Pubmed , Embase and ISI database (1970-01-2013-08 ).The amount of literature , publication date , au-thors, languages, article types, epidemiology, molecular mechanisms of re-sistance and treatment were analyzed.Results A total of 257 papers were included, 10 reviews, 4 conference article , 233 article.The first report was in 2001 and the amount of publications increased yearly.Conclusion KPC-producing Klebsiella pneumoniae was apparently wild spread in the world.Research of KPC-producing Klebsiella pneumoniae was studied deeply.