利用组织工程技术制备神经支架应用于神经系统损伤的修复已经成为神经系统再生研究领域的重点,其中利用生物材料以微球体形式,持续缓慢释放活性物质,有利于神经系统再生的微环境改善,也是研究的热点。本文就微球体制备的相关材料、制备方法、检测及在神经系统损伤修复中的作用等进行综述,并进行了总结和展望。
Tissue engineering technology has been applied to prepare nerve conduits for repairing nervous system's injury and has become the focus in the field of nervous system' s regeneration. Using biological materials in the form of microspheres has become main issues. Microspheres can release bioactive substances in a sustained and controlled manner,they improve the microenvironment of nervous system' s regeneration. This paper reviews candidate materials,fabrication techniques,and detection methods for preparing microspheres and discuss the role of microspheres in nervous system's injury and repair.