骨形成过程受多种因素的调节,包括激素、细胞因子、生长因子等。其调控方式是由复杂的信号分子及其相连的信号通路实现的,因此,信号通路在其中的作用是当前研究的热点,该文综述了cAMP、cGMP信号通路调节骨形成的研究进展。
The bone formation is regulated by multiple elements including hormones,cytokines,growth factors,etc,and the regulation of this process is carried out by complex molecules through different signaling pathways.Therefore,the role of signaling pathways is the current focus of research.How cAMP,cGMP signaling pathways regulate bone formation is reviewed in this paper.