多溴联苯醚(polybrominated diphenyl ethers,PBDEs)是一种非常优质的阻燃剂,在日常生活中有广泛的应用,但由于PBDE及其代谢产物OH-PBDEs具有扰乱甲状腺素作用而被研究学者关注。本文对PBDEs和OH-PBDEs引起的早期胚胎毒性及对去碘酶的影响作了相关综述。
Polybrominated diphenyl ethers (PBDEs) and their metabolites (hydroxylated PBDEs) are excellent flame retardants and have wide applications in daily life, but it has been concerned that most of these chemicals are endocrine disruptor damaging the function of thyroid hormone. The toxicity of PBDEs and OH-PBDEs on embryos at early development and the effects on deiodinase were summarized in this review.