猪肉的产量和质量与肌肉发育过程紧密相关。肌肉发育包括胚胎期肌纤维的形成、出生后肌纤维的发育和成年期肌肉的再生等步骤,该过程受到转录水平、转录后水平及通路水平等多层次的网络调控。本文以猪肌肉发育过程为切入点,重点讨论了调控猪肌肉发育的分子基础和高瘦肉率基因改良猪的研究进展,为进一步培育优质猪肉和高瘦肉率猪品种提供了参考。
The production and quality of pork is closely related to muscle development. Muscle development needs to undergo several steps: The formation of prenatal muscle fiber, the differentiation and enlongation of postnatal muscle fiber and the renewal of adult muscle. The myogenesis process is controled by a complicated network, including tanscriptional, post-transcriptional regulation and several pathways. Starting from the process of porcine myogenesis, we will mainly discuss the molecular mechanism of myogenesis regulation and the transgenetic pigs for pork improvement in this review, which will provide the basis for cultivating pigs with high lean meat percentage and obtianing pork of high quality.