中文摘要：

本文利用已测序的157个滇金丝猴控制区（D-loop）片段,通过与参考序列比对,鉴别了线粒体D-loop片段中的52个SNP（Single Nucleotide Polymorphisms）位点,定义了30种滇金丝猴单倍型,排除概率为0.938。谱系及种群遗传结构分析结果与以前利用D-loop片段的研究结果相似。同时表明基于粪便样品进行保护遗传学、谱系生物地理学、种群遗传学等研究时,与线粒体标记和微卫星标记相比,SNP标记可能具有一定的优越性,并建议进一步分析滇金丝猴线粒体D-loop全序列甚至线粒体全基因组上的SNPs位点的信息,以促进滇金丝猴保护遗传学等研究的开展。

英文摘要：

Based on alignment of mtDNA D-Loop 401 bp of Rhinopithecus bieti and comparison with a standard sequence,30 haplotypes and 52 single nucleotide polymorphisms（SNPs） were identified among 157 individuals,and the probability of exclusion was found to be 0.938.The phylogeographic patterns and population genetic structure based on SNP analysis were similar to those using mtDNA D-Loop sequence analysis.The results also indicated that SNP marker might be superior to mtDNA and microsatellite markers when studies on conservation genetics,phylogeography and population genetics are conducted using fecal samples.Thus,we suggest that more powerful SNPs should be further identified from complete Dloop or whole mitochondrial genome of R.bieti in the future.