中文摘要：

检测分离获得的43株海洋细菌的群体感应信号分子及生物膜形成能力,评估细菌群体感应信号分子与生物膜形成能力之间的关系.结果显示,高丝氨酸内酯类化合物活性菌株（10株）中90%的菌株（9株）有很强的生物膜形成能力,且10株中的7株（70%）所形成的生物膜存在明显的细胞团.具有AI-2活性的菌株中67%的菌株具有较强的生物膜形成能力.结果中具有AHLs活性的菌株往往形成强的生物膜,并常能形成较大的细胞团.许多不能产生群体感应信号分子的菌株也具有较强的生物膜形成能力,可见对于环境细菌,群体感应信号分子的存在特别是AHLs的存在,趋向于是细菌生物膜形成的充分非必要条件.

英文摘要：

In this study,the correlation between quorum sensing and biofilm forming of 43 marine bacterial strains was evaluated by quantitatively detecting the activity of acyl-homoserine lactones（AHLs） and AI-2 signals,as well as the biofilm formation in the 43 bacterial strains.The results revealed that 9 of the 10（90%） AHL activity strains displayed definite biofilm-forming capacity,7 of these 10 strains exhibited highly structured architecture in biofilm.67% of AI-2 activity strains have strong biofilm-forming capacity.The results also indicated that the strains with AHL activity usually presented strong biofilm-forming capacity.However,other bacteria which cannot produce quorum sensing signal still exhibit strong biofilm-forming capacity.Therefore,it could be indicated that for environmental bacteria,the existing of quorum sensing signal molecule（especially the AHL） in bacterial strains,usually tends to be a sufficient condition other than a necessary one for forming biofilms