中文摘要：

目的：研究当归地上部分的化学成分和抗凝血以及抗菌活性成分。方法：采用多种柱层析方法进行分离纯化：根据波谱解析和理化鉴别鉴定其结构；采用凝血酶时间法测试化合物的抗凝血活性，采用连续二倍稀释法测试化合物的抗菌活性。结果：从当归地上部分分离得到13个化合物，分别鉴定为：24，24．二甲基-9，19-环羊毛甾烷-3-β-醇（1），β-谷甾醇（2），2，3，6-三甲基苯甲酸（3），尿嘧啶（4），胡萝卜苷（5），金丝桃苷（6），尿囊素（7），甘露醇（8），1S-（4＇-羟苯基）-1，2-乙二醇（9），咖啡酸（10），绿原酸（11），蔗糖（12），D-葡萄糖（13）。化合物3，4，6，7，9，10和11能显著延长凝血酶时间。化合物1，4，6，7和9显著抑制嗜水气单胞菌的生长。结论：化合物1，3，6-9为首次从该种植物中得到；化合物1，3，4，6，7，9-11为当归地上部分重要的活性成分。

英文摘要：

AIM： To investigate the chemical constituents from the aerial parts of Angelica sinensis and their anticoagulative and antibiotic activities. METHODS： The constituents of the 80% ethanol extract were isolated and purified by various chromatographic methods. Their structures were identified by the physicochemical characteristic and spectral data. The anticoagulative activity of the isolated compounds were tested using the thrombin time method assay, and the antibiotic activity were tested using the serial two-fold dilution method. RESULTS： Thirteen known compounds were isolated and identified as 24, 24-dimethyl-9,19-cyclolanostan-3β-ol （1）, β-sitosterol （2）, 2, 3, 6-trimethylbenzoic acid （3）, uracil （4）, daucosterol （5）, hyperoside （6）, allantoin （7）, D-mannitol （8）, 1S-（4＇-hydroxyphenyl）-l, 2-ethanediol （9）, caffeic acid （10）, chlorogenic acid （11）, sucrose （12） and D-glucose （13）. Compounds 3, 4, 6, 7, 9, 10 and 11 moderately prolonged thrombin time. Compounds 1, 4, 6, 7 and 9 significantly inhibited the growth of Aeromohas hydrophila. CONCLUSION： Compounds 1, 3, 6-9 were isolated from this plant for the first time. Compounds 1, 3, 4, 6, 7, 9, 10 and 11 are the important active constituents of the aerial parts of Angelica sinensis.