中文摘要：

脂肪干细胞是存在于脂肪组织中的一种成体干细胞，具有来源丰富、可反复取材、痛苦小、易扩增、能安全植入同体或异体等优点，已成为组织工程理想的种子细胞。基于其多潜能分化和旁分泌功能，新近认为是继胚胎干细胞、骨髓干细胞之后的又一热点。已发现脂肪干细胞及其可溶性因子具有促进伤口愈合、促进成纤维细胞增殖、抗氧化、抗皱纹、美白皮肤等作用，在皮肤抗衰老领域有应用潜力。

英文摘要：

Adipose-derived stem cells （ADSCs） are a kind of adult stem cells in the adipose tissue. They have many advantages, such as being easy to acquire, allowing repetitive sampling with little pain, safe autotransplantation or allotransplantation, and propagating easily, which have made them an ideal cell source for tissue engineering. For the muhi-lineage differentiation potential and paracrine function, they have become another hot topic after embryonic stem cells and bone marrow stem cells in the field of cell therapy. It has been found that ADSCs have antioxidant, anti-wrinkle and anti-melanogenie activity, and they themselves together with their soluble factors can promote wound healing and fibroblast proliferation. Therefore, ADSCs have the potential to treat skin aging.