巨噬细胞被认为是创面愈合和组织修复过程的“总指挥”,在愈合过程中,巨噬细胞胞葬与表型转换并不是两个独立的生物学过程,二者之间存在着必然的联系,胞葬作用机制的受损将影响巨噬细胞表型的转换,导致慢性炎性反应的发生。
Macrophages play a central role in all stages of wound healing and orchestrate the wound healing process. Efferocytosis and phenotype transition are not two independent biological processes, but have the connec- tion and potential relationship. The phagocytosis of neutrophils influences macrophage phenotype, causing the chro- nic inflammation.