中文摘要：

本文报道了一种合成麦角生物碱fumigaclavines A–D四环骨架的新方法,利用钯催化的分子内Larock吲哚合成一步即构筑了四环核心骨架的B/C环。尽管将化合物18转化生成fumigaclavine B的所有尝试失败,本研究为fumigaclavines A–D的全合成做了有益的探索。

英文摘要：

In the present study, we developed a novel approach for the synthesis of the tetracyclic core of fumigaclavines A–D. A palladium-catalyzed intramolecular Larock indole synthesis was utilized to assemble the B/C rings of the tetracyclic core in one step. Although all attempts to convert compound 18 to fumigaclavine B failed, this study provided useful information for the total synthesis of fumigaclavines A–D.