为了研究对控制后肢运动的脊髓神经信号的追踪方法,设计了一种跟踪监测大鼠脊髓神经信号传导通路的实验方案。首先采用串脉冲对大鼠运动皮层代表区进行刺激,确定诱发对侧后肢运动的皮层区域;然后电刺激该脑皮层功能区,在脊髓上用只有针尖裸露的针电极多点监测和记录脊髓神经信号,利用幅值对比方法确定控制后肢运动的脊髓神经信号传导路径中的有效位点。经相干性分析得到两有效传输位点间信号的相干函数值为0.9918,证明了这两个信号高度相关;并计算得到控制下肢运动的脊髓神经信号的传导速度约为40m/s。结果表明这种电子信息学方法追踪控制后肢运动的神经信号在脊髓中的传导路径是可行的。
An experimental scheme for monitoring the rat was designed to study a method for tracking cord with an electronic way. Firstly, a train of conductive the neural s pathway of the neural signals in the spinal cord of the ignals controlling the hindlimb movement in the spinal bipolar pulses was used to stimulate the motor cortical representa- tions of the rat to determine the relative location inducing contralateral hindlimb movement. Then, electrical stimu- lation was used to stimulate the functional areas determined in the last step and the neural signals in the spinal cord was monitored and recorded multipointly with the electrode which exposed only the tip. Amplitude comparison was used to determine the effective points in the conductive pathway of the neural signals controlling the hindlimb move- ment in the spinal cord. Correlation analysis was used to determine the relevance between the two points in the con- ductive pathway of the spinal cord. The cross-correlation function reached the value of 0. 9918, which proved that the two signals were highly correlated. The conduction velocity of the neural signals controlling the hindlimb move- ment was 40m/s. The results show that this method of tracking neural signals in the spinal cord which control hind- limb movements in an electronic information way is feasible.