欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
血小板通过与中性粒细胞、单核细胞及血管内皮细胞相互作用后,参与动脉粥样硬化、卒中及哮喘等病理过程。近年来,一种新的非编码RNA,称为微小RNAs（miRNAs）,在细胞增殖、分化和凋亡等生物过程中扮演重要的角色。血小板自身含有丰富的miRNAs,研究表明,miRNAs调控血小板的功能,进而影响多种疾病的发生发展。本文就血小板miRNAs对血小板产生和激活调控机制的研究进展作一综述。
英文摘要：
Platelets play a important role in atherosclerosis,stroke and asthma through active interaction with neutrophils,monocytes,and vascular endothelial cells.Recently,the novel class of noncoding RNAs,known as microRNAs（miRNAs）,have been demonstrated to play crucial roles in diverse biological processes including development,cell differentiation and apoptosis.Platelets express abundant miRNAs.In the past few years,the scientific community has produced remarkeable advances in our understanding of miRNAs that are involved in function of platelet and of their profound effects on various diseases.Here,we review the current understanding about the regulatory mechanisms of platelet miRNAs on platelet production and activation.
同期刊论文项目
同项目期刊论文
New population-based exome data question the pathogenicity of some genetic variants previously assoc
PPAR gamma Ligands Decrease Hydrostatic Pressure-Induced Platelet Aggregation and Proinflammatory Ac
Should Aspirin Be Used for the Primary Prevention of Cardiovascular Disease in the General Populatio
Invasive Management of Acute Coronary Syndrome in Patients End-stage Renal Disease: a Meta-analysis2
期刊信息
位置：