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Cyclooxygenase 2 1195G〉A polymorphism is associated with chronic obstructive pulmonary disease in Japanese and Chinese patients

ISSN号：0366-6999
期刊名称：《中华医学杂志：英文版》
分类：Q555[生物学—生物化学] Q987[生物学—遗传学;生物学—人类学]
作者机构：[1]Department of Internal Medicine, Division of Clinical Oncology & Respiratory Medicine Shimane University Faculty of Medicine, 89-1, Enya cho, Izumo, Shimane 6938501, Japan, [2]Department of Respiratory Medicine, Second Affiliated Hospitalof Ning Xia Medical University, Yinchuan, Ningxia 750001, China, [3]Department of Dermatology Shimane University Faculty of Medicine, 89-1, Enyacho, Izumo, Shimane 6938501, Japan
相关基金：This study was supported by grants from Shimane University Hospital （Shimane, Japan）, National Natural Science Fundation of China （No. 81060005） and Natural Science Funds of Ningxia （No. NZ09165）.Acknowledgments： The authors would like to be grateful to the Japanese and Chinese partners who helped collecting the blood samples for the study. We also thank all the study subjects as well as all other staffwho participated in this study.

作者： CHEN Li-jun[1], XU Wang[2], Yasuyuki Taooka[1], Miki Ohe[1], Hitoshi Takahashi[3], Akihisa Sutani[1], Takashige Kuraki[1], Takeshi Isobe[1]

关键词：慢性阻塞性肺病, 单核苷酸多态性, 环氧合酶-2, 中国人, 日本, 患者, 慢性阻塞性肺疾病, 限制性片段长度多态性, cyclooxygenase-2, polymorphisms, chronic obstructive pulmonary disease, Japanese, Chinese

中文摘要：

Correspondence to： Dr. Takeshi Isobe, Department of Internal Medicine, Division of Clinical Oncology ＆ Respiratory Medicine, Shimane University Faculty of Medicine, 89-1, Enya cho, Izumo, Shimane 693 8501, Japan （Tel： 81-853-20-2580. Fax： 81-853-20- 2580. Email： isobeti@med.shimane u.ac.jp）

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