中文摘要：

生长轴是动物体内下丘脑-垂体-靶器官一系列激素及其受体所组成的神经内分泌系统。通过提高生长轴中生长激素（GH）和胰岛素样生长因子-Ⅰ（IGF-Ⅰ）水平,促进增重、提高饲料转化率和改善肉品质,是畜禽生长调控的一种新途径。GH通过IGF-Ⅰ介导调节动物生长和细胞分化等,文章综述了GH/IGF-Ⅰ轴的组成、功能,以及GH调控IGF-Ⅰ表达的分子机理。

英文摘要：

The growth axis is a neuroendocrine system,which is composed of series of hormones and their receptors from the hypothalamus-pituitary-target organ in vivo of animals.Increasing the GH and IGF-Ⅰ levels in the growth axis,to promote weight gain,feed conversion rate and improve meat quality,which is a new approach of animal growth regulation.GH mediated by IGF-Ⅰ regulates animal growth and cell differentiation.We will discuss the constitution and function of GH/IGF-Ⅰ axis,and mechanism of growth hormone regulation of IGF-Ⅰ expression in this review.