近年来,细胞内钙离子信号及其产生机理已成为研究热点之一,这是因为钙离子信号能控制细胞的生死、传递细胞间的信息、提高基因表达的有效性和特殊性、在钙离子信号传递过程中,受环境扰动是不可避免的.Shuai等川发现噪音能够控制钙离子通道中钙离子的释放.在过去的十年中,无论是物理、化学还是生物体系的噪音效应已被广泛研究,其中包括对随机共振(SR)的研究。
The dynamic behavior of calcium ion oscillations was investigated when noise was injected to the system located in a steady state and an oscillatory state, respectively. It was found that noise can contribute to phenomenon of implicit or explicit internal stochastic resonance (IISR or EISR) , and that distance to bifurcation point was a key factor for controlling IISR or EISR. Then an external signal was added to the system, the result shows that IISR or EISR can not occur, implying an external signal destroys the cooperation of internal signal and noise. Furthermore, the difference and the similarity were discussed between IISR and EISR.