中文摘要：

采用反相悬浮乳液法合成了丙烯酸（AA）含量不同的N-异丙基丙烯酰胺（NIPAM）共聚丙烯酸（AA）的聚合物模板P（NIPAM-co-AA）,以此作为微反应器,分别用两种不同的方法制备了P（NIPAM-co-AA）-co-Alq3（八羟基喹啉铝）荧光复合微球,再用四乙氧基硅烷（TEOS）对其表面进行修饰,获得了表面功能化的P（NIPAM-co-AA）-Alq3-SiO2荧光复合微球。用SEM、IR、FM和XRD等手段对其结构和性能进行表征。结果表明：所制备的荧光复合微球单分散性好、荧光发光效率较高且性能稳定,同时具有较大的比表面积;功能化的荧光复合微球可用于高通量药物筛选和识别生物大分子等生物医学领域。

英文摘要：

N-isopropylacrylamide（NIPAM） and acrylic acid（AA）copolymer microspheres with various compositions were prepared by a reverse suspension emulsion technique.The microspheres were employed as microreactors for the synthesis of fluorescence composite microspheres by two different methods.In this way,several uniform of P（NIPAM-co-AA）-Alq3 fluorescence composite microspheres were prepared.The surface functionalized P（NIPAM-co-AA）-Alq3-SiO2 fluorescence composite microspheres was prepared by decorating the surface with the tetraethoxy-silicone（TEOS）.The fluorescence composite microspheres were characterized by SEM,IR,FM and XRD.The results indicate uniform particle size fluorescent composite microspheres are obtained with high efficiency fluorescent light and high specific surface area.It might be expected that this functional material can be applied for high-throughput screening assays and recognition of biomacromolecules in biological medical fields.