衣原体是引起多种人类疾病的专性胞内寄生的革兰阴性菌。接种疫苗是预防和控制衣原体感染的经济有效的途径。目前,衣原体疫苗的研究主要集中在亚单位疫苗、载体疫苗、DNA疫苗等,这些疫苗往往需要免疫佐剂来增强其免疫效果。现就佐剂在衣原体疫苗中应用的研究进展作一综述。
Chlamydiae are obligate intracellular Gram-negative bacteria that cause widespread diseases in humans. Vaccination is the most economical and effective way to control chlamydial infections. At present,the main kinds of chlamydial vaccine include subunit vaccine,vector vaccine,DNA vaccine,and so on. These vaccines often require adjuvants to enhance the immune effects. The progress of adjuvants in the applications of chlamydial vaccine are discussed.