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中文摘要：
本项目通过食品安全复杂样品体系的分离与检测新技术、新方法的研究，为提高我国食品安全技术水平提供理论基础与技术支撑，其最终目的是促进解决以下问题1）食源性危害的关键检测技术问题；2）食源性疾病与危害的监测、溯源和预警技术问题；3）食品安全标准的基础研究，推行"良好农业规范（GAP）"和"危害关键控制点分析（HACCP）"问题。为此，本项目拟开展以下几个方面的研究（1）采用分子印迹聚合物制备技术及有机改性sol-gel技术制备具有纳米孔洞结构及生物分子识别功能的毛细管电色谱整体柱；（2）开展基于微固相萃取的食品安全复杂样品前处理技术研究；（3）开展毛细管电泳/电色谱-电化学/化学发光/电致化学发光检测联用技术研究；（4）开展毛细管电泳/电色谱-质谱检测联用技术研究；（5）将上述技术用于食品安全复杂样品体系中农药残留、抗生素、激素、食品添加剂和贝类/澡类毒素等污染要素的分离和高通量快速检测。
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期刊论文
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期刊论文
Analysis of aliphatic amines using head-column field-enhanced sample stacking in micellar electrokin
Rapid analysis of peptides and amino acids by CE-ESI-MS using chemically modified fused silica capil
Sequence specific detection of trace DNA via a junction-probe electrochemical sensor employed templa
A electrochemiluminescent sensor for methamphetamine hydrochloride based on multiwall carbon nanotub
Determination of estrogens in wastewater using three-phase hollow fiber-mediated liquid-phase microe
Separation and determination of enkephalin-related peptides by capillary electrophoresis with ampero
ZnO Nanorod Array Solid Phase Micro-extraction Fiber Coating: Fabrication and Extraction Capability”
ZnO nanorod array polydimethylsiloxane composite solid phase micro-extraction fiber coating: fabrica
Speciation analysis of arsenic in Mya arenaria Linnaeus and Shrimp with capillary electrophoresis-in
An online field-amplification sample stacking method for determination of diuretics in urine using c
GoldMag nanocomposites-functionalized graphene sensing platform for one-step electrochemical immunoa
Development of ultra-high sensitive and selective electrochemiluminescent sensor for copper(II) ions
Electrochemiluminescent behavior of Tris(2,2-bipyridine) ruthenium(II)/ triethylamine in Ionic Liqui
Gold-silver-graphene hybrid nanosheets-based sensors for sensitive amperometric immunoassay of alpha
Synthesis and applications of diethylstilbestrol-based molecularly imprinted polymer-coated hollow f
Single-walled carbon nanotubes coated fibers for solid-phase microextraction and gas chromatography–
Highly sensitive transient isotachophoresis sample stacking coupling with capillary electrophoresis-
A new method for the analysis of (2-agonists in human urine by pressure-assisted capillary electroch
Nanoparticle-Based Sandwich Electrochemical Immunoassay for Carbohydrate Antigen 125 with Signal Enh
On-line coupling pressure-assisted capillary electrochro-matography with electrospray ionization mas
Ultrasensitive electrochemical immunoassay of staphylococcal enterotoxin B in food using enzyme-nano
Applications of capillary electrophoresis and microchip capillary electrophoresis for detection of g
Molecularly imprinted polymer as SPE sorbent for selective extraction of melamine in dairy products,
A new interface used to couple capillary electrophoresis with an inductively coupled plasma mass spe
A Strategy for Development of Ultrahighly Sensitive and Selective Electrochemical DNA Sensor via Nic
Capillary electrophoresis with electrochemiluminescent detection for highly sensitive assay of genet
Sensitive electrochemical immunoassay of carcinoembryonic antigen with signal dual-amplification usi
An enzyme-free quartz crystal microbalance biosensor for sensitive glucose detection in biological f
Determination of Copper(II) Ion in the Dairy Product by an Electrochemical Sensor Based on Click Che
Electrochemical and in situ SERS Studies on Adsorption of 2-hydroxypyridine and Polyethyleneimine du
Highly Sensitive Electrochemiluminescennt Sensor for Adenosine Based on Structure-Switching of Aptam
Fabrication of a new electrochemiluminescent sensor for fentanyl citrate based on glassy carbon micr
Electrochemiluminescent biosensor for superoxide dimutase based on multi-wall carbon nanotube/Nano-A
Preparation and application of solid-phase microextraction fiber based on molecularly imprinted poly
Label-free electrochemiluminescent immunosensor for α-fetoprotein: performance of Nafion-carbon nano
Simultaneous determination of five-type hepatitis virus antigens in five minutes using an integrated
Electrostacking online sample pre-concentration capillary electrophoresis with amperometric detectio
Determination of Botanical Insecticides Residues in Fish by Liquid Chromatography-Electrospray Tande
Improved simultaneous enantioseparation of β-agonists in capillary electrophoresis using β-cyclodext
Assay of bradykinin metabolites in human body fluids by CE-LIF coupled with transient isotachophores
Enantiomeric separation of chiral dipeptides by CE-ESI-MS employing a partial filling technique with
Study on the photodegradation and microbiological degradation of pirimicarb insecticide by using liq
Rapid hydrolysis and electrochemical detection of trace carbofuran at a disposable heated screen-pri
Enhanced electrochemiluminescence of luminol-O2 system at gold–hydrophobic ionic liquid|water interf
Signal-on electrochemiluminescence biosensor for thrombin based on target-induced conjunction of spl
On-line preconcentration and quantitative analysis of peptide hormone of brain and intestine using o
Assay of bradykinin- related peptides in human body fluids using capillary electrophoresis with lase
A Strategy for Development of Electrochemical DNA Biosensor based on Site-specific DNA Cleavage of R
Analysis of Methylene Blue and Its Metabolites in Blood by Capillary Electrophoresis/Electrospray Io
pCEC coupling with ESI-MS for the analysis of (2-agonists and narcotics using a poly(1-hexadecene-co
Determination of diuretics in human urine by hollow fiber based liquid-liquid-liquid microextraction
Ultrasensitive aptamer-based multiplexed electrochemical detection by coupling distinguishable signa
A novel Tb3+-promoted G-quadruplex-hemin DNAzyme for the development of label-free visual biosensors
Magneto-controlled electrochemical immunosensor for direct detection of squamous cell carcinoma anti
Synthesis of a new Ni-phenanthroline complex and its application as anelectrochemical probe for dete
Preparation of reversible colorimetric temperature nanosensors and their application in quantitative
Synthesis of Magnetic Nanoparticles with Immobilized Aminophenylboronic Acid for Selective Separatio
Separation and determination of flavonoids using microemulsion electrokinetic chromatography with el
Determination of aromatic amines in environmental water sample by hollow fiber-liquid phase microext
Highly enhanced electrocatalytic oxidation of shikimic acid at a disposable electrically heated oxid
An improved facile method for extraction and determination of steroidal saponins in Tribulus terrest
A highly sensitive and selective sensing ECL platform for naringin based on β-Cyclodextrin functiona
One-pot synthesis of organic-inorganic hybrid affinity monolithic column for specific capture of gly
Dynamic pH junction- Sweeping for on-line focusing of dipeptides in capillary electrophoresis with l
Controllable Preferential-etching Synthesis of ZnO Nanotubes Array on SiO2 Substrate for Solid-phase
An electrochemical biosensor for detection of BCR/ABL fusion gene using locked nucleic acids on 4-am
Capillary electrophoresis with electrochemiluminescence detection: fundamental theory, apparatus, an
Analysis of ultratrace triorganotin compounds in aquatic organisms by using capillary electrophoresi
Analysis of microcystins by capillary zone electrophoresis coupling with electrospray ionization mas
Label-Free Detection of Telomerase Activity in HeLa Cells Using Electrochemical Impedance Spectrosco
Determination of the epimerization rate constant of amygdalin by microemulsion electrokinetic chroma
Study on seafood volatile profile characteristics during storage and its potential use for freshness
Nanogold-actuated biomimetic peroxidase for sensitized electrochemical immunoassay of carcinoembryon
A novel approach based on ferricyanide-mediator immobilized in an ion-exchangeable biosensing film f
A highly performing electrochemical sensor for NADH based on gragphite/Poly (methylmethacrylate) com
Analysis of (-agonists and (-blockers in urine using hollow fibre-protected liquid-phase microextrac
Design of a DNA electronic logic gate (INHIBIT gate) with an assayingapplication for Ag+ and cystein
An Ultrasensitive Electrochemical Biosensor for Detection of DNA Species Related to Oral Cancer base
An extremely stable and sensitive end-column electrochemical detector based on heated copper microdi
Study on interaction between a new fluorescent probe 2-methylbenzo[b][1,10] phenanthrolin-7(12H)-one
An Ultrasensitive and Selective Electrochemiluminescent Sensor for detection of Trace Copper(II) Ion
Sensitive turn-on fluorescent detection of melamine based on fluorescence resonance energy transfer,
Label-free fluorescent sensor for mercury(II) ion by using carbon nanotubes to reduce background-sig
Specific immunoreaction-induced controlled release strategy for sensitive impedance immunoassay of c
Gold nanoparticles for highly sensitive and selective copper ions sensing-old materials with new tri
Electrogenerated Chemiluminescence Emissions from CdS Nanoparticles for Probing of Surface Oxidation
G-quadruplex DNAzyme as the Turn on Switch for Fluorimetric Detection of Genetically Modified organi
Increasing the Sensitivity and Single-Base Mismatch Selectivity of the Molecular Beacon using Graphe
Synthesis of a new Ni-phenanthroline complex and its application as electrochemical probe for detect
Electrochemical impedance spectroscopy sensor for ascorbic acid based oncopper(I) catalyzed click ch
Microemulsion electrokinetic chromatography coupling with field amplified sample injection and elect
A Simple “Molecular Beacon”-Based Fluorescent Sensing Strategy for Sensitive and Selective Detection
Strong electrochemiluminescence based on electron transfer between Tris(2,2′-bipyridine)ruthenium(II
Synthesis of “Clean” and Well-Dispersive Pd Nanoparticles with Excellent Electrocatalytic Property o
A sweeping-micellar electrokinetic chromatography method for direct detection of some aromatic amine
Determination of organophosphorus pesticides by capillary electrophoresis-inductively coupled plasma
Nonenzymatic amperometric sensing of glucose by using palladium nanoparticles supported on functiona
An electrochemiluminescent detection system equipped with an electrically heated indium-tin-oxide el
An electrochemiluminescent biosensor for uric acid based on the electrochemiluminescence of bis-[3,4
A novel electrochemiluminescence sensor based on bis(2,2′-bipyridine)-5-amino-1,10-phenanthroline ru
Electrochemiluminescence of Water-Soluble Carbon Nanocrystals Released Electrochemically from Graphi
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