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中文摘要：
分子组装是提供新物质并赋予其特殊理化功能的重要技术源泉之一。因此，结构新颖的分子组装体的构筑及构效关系就成为超分子化学的核心研究内容。该项目拟以具有疏水腔的环糊精、杯芳烃、葫芦脲等环状分子为媒介，通过非共价键力的协同相互作用将它们与富勒烯等碳基材料，卟啉、酞菁等光活性分子，生物碱、ATP、蛋白质等生物分子及顺铂衍生物、紫杉醇、喜树碱、阿霉素等药物分子构筑成几个系列结构新颖的分子组装体，运用各种现代测试技术研究分子组装体的结构和组装机制，采用量热滴定和停流等方法研究自组装过程的热力学起源和动力学控制因素，进而考查从小分子到多重分子组装体的多级组装过程、构效关系等基本科学问题。通过对组装方法的不断优化实现对分子组装体的调控，阐述组装体的微观结构和宏观性能之间的关系，开拓具有生物等功能为导向的分子组装技术，推动自组装的可逆调控和功能化进程，并在此基础上揭示新现象，发展新理论，开拓新技术。
结论摘要：
英文主题词cyclic molecules；molecular assembly；hydrophobic cavity；structure-activity relationship；supramolecular chemistry
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期刊论文
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Light-controlled reversible formation and dissociation of nanorods via interconversion of pseudorota
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