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新型生物医学探针技术基础及应用
项目名称:新型生物医学探针技术基础及应用
项目类别:创新研究群体科学基金
批准号:20921062
申请代码:B05
项目来源:国家自然科学基金
研究期限:2010-01-01-2012-12-31
项目负责人:庞代文
负责人职称:教授
依托单位:武汉大学
批准年度:2009
中文摘要:
中文主题词探针;生物分析;方法;检测;肿瘤
中文主题词:
英文摘要:
probe;bioanalysis;method;detection;tumor
英文主题词:
probe;bioanalysis;method;detection;tumor
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期刊论文
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260
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期刊论文
金纳米粒子作探针共振瑞利散射光谱法测定牛奶中三聚氰胺
Preparation of magnetic polymer material with phosphate group and its application to the enrichment
Conformation and Thermodynamic Properties of the Binding of Vitamin C to Human Serum Albumin
Enhanced photocatalytic activities of TiO2 nanocomposites doped with water-soluble mercapto-capped C
Solidified floating organic drop microextraction combined with ETV-ICP-MS for the determination of t
Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives
Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: lab
Effect of Combustion Improver on Combustion Behavior of Cigarette Paper by Simultaneous TG/DSC Detec
Studies of the Activity of Peroxidase-Like DNAzyme by Modifying 3 '- or 5 '-End of Aptamers
Hepatocellular carcinoma: insight from animal models
Investigation of the Interaction Between Ofloxacin and Bovine Serum Albumin: Spectroscopic Approach
Magnetic solid phase microextraction on a microchip combined with electrothermal vaporization-induct
Hollow fiber-liquid phase microextraction combined with gas chromatography for the determination of
微量热法在药物活性评价中的应用
Affinity and Specificity of Ciprofloxacin-Bovine Serum Albumin Interactions: Spectroscopic Approach
Borated titania, a new option for enrichment of cis-diol biomolecules
Ultrasmall Near-Infrared Ag2Se Quantum Dots with Tunable Fluorescence for in Vivo Imaging
Tandem Solid Phase Extraction Followed by Online Trapping-Hydrophilic Interaction Chromatography-Tan
Interaction of human serum albumin with 10-hydroxycamptothecin: spectroscopic and molecular modeling
Carbohydrate antigen 242 highly consists with carbohydrate antigen 19-9 in diagnosis and prognosis o
A graphene oxide-based fluorescent aptasensor for the turn-on detection of epithelial tumor marker m
Immobilization of Escherichia coli for detection of phage T4 using surface plasmon resonance
Zirconia coated stir bar sorptive extraction combined with large volume sample stacking capillary el
Construction of CdSe/ZnS quantum dot microarray in a microfluidic chip
Dual-Color Imaging of Magnesium/Calcium Ion Activities with Two-Photon Fluorescent Probes
Preparation of Hyper-cross-linked Polymer Monolithic Column and Its Application on the Sensitive Det
Determination of Estrogens in Pork and Chicken Samples by Stir Bar Sorptive Extraction Combined with
Spectroscopic studies on the interaction of bovine serum albumin with surfactants and apigenin
Controlled synthesis of NaYF4: Yb, Er nanocrystals with upconversion fluorescence via a facile hydro
Sensitive determination of phenylarsenic compounds based on a dual preconcentration method with capi
Membrane solid phase microextraction with alumina hollow fiber on line coupled with ICP-OES for the
Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Improves Survival of Patients wi
Patterns of cancer invasion revealed by QDs-based quantitative multiplexed imaging of tumor microenv
Preoperative Serum Carbohydrate Antigen 242 Is a Useful Predictive and Prognostic Marker in Colorect
Magnetic solid-phase extraction based on magnetic carbon nanotube for the determination of estrogens
Immunomagnetic assay combined with CdSe/ZnS amplification of chemiluminescence for the detection of
In situ spectral imaging of marker proteins in gastric cancer with near-infrared and visible quantum
Effect of Ce(III) on Heat Production of Mitochondria Isolated from Hybrid Rice
Rapid Determination of Estrogens in Milk Samples Based on Magnetite Nanoparticles/Polypyrrole Magnet
Determination of huperzine A in human plasma by hydrophilic interaction chromatography coupled to ta
Application of liquid phase deposited titania nanoparticles on silica spheres to phosphopeptide enri
A reaction-based chromogenic and fluorescent chemodosimeter for fluoride anions
Determination of brain cytochrome P450 2E1 activity in rat with the probe of chlorzoxazone by liquid
基于Hoechst33258荧光染料检测单链DNA的方法研究
Grafting of silica with a hydrophilic triol acrylamide polymer via surface-initiated"grafting f
Phase transfer membrane supported liquid-liquid-liquid microextraction combined with large volume sa
Biophysical studies of the interaction between a triazole derivative and bovine serum albumin by mul
Spectroscopic and Molecular Modeling Studies on the Interaction Between a Fluorine-Containing Triazo
Development and Evaluation of a Rotary Cell for Capillary Electrophoresis-Chemiluminescence Detectio
Binding of berberine to bovine serum albumin: spectroscopic approach
Polymer monolith-integrated multilayer poly(dimethylsiloxane) microchip for online microextraction a
Titania coated magnetic mesoporous hollow silica microspheres: fabrication and application to select
Immunoaffinity monolithic capillary microextraction coupled with ICP-MS for immunoassay with quantum
Synergistic gastric cancer inhibition by chemogenetherapy with recombinant human adenovirus p53 and
The use of liquid phase deposition prepared phosphonate grafted silica nanoparticle-deposited capill
Characterize the interaction between naringenin and bovine serum albumin using spectroscopic approac
On-line separation/preconcentration of V(IV)/V(V) in environmental water samples with CTAB-modified
Detection of EBV in nasopharyngeal carcinoma by quantum dot fluorescent in situ hybridization
Interaction of coomassie brilliant blue G250 with human serum albumin: Probing of the binding mechan
Coronin-1C is a novel biomarker for hepatocellular carcinoma invasive progression identified by prot
荧光探针Ru(phen)2dppx2+测定H1N1禽流感病毒DNA研究
Thermo-responsive polymer coated fiber-in-tube capillary microextraction and its application to on-l
Energy-Level-Related Response of Cathodic Electrogenerated-Chemiluminescence of Self-Assembled CdSe/
Preoperative serum carbohydrate antigen 125 level is an independent negative prognostic marker for o
Determination of some refractory elements and Pb by fluorination assisted electrothermal vaporizatio
High Ki-67 Expression is a Poor Prognostic Indicator of 5-Year Survival in Patients with Invasive Br
Quantum dots-based double-color imaging of HER2 positive breast cancer invasion
Magnetic retrieval of graphene: Extraction of sulfonamide antibiotics from environmental water sampl
Quantum dots-based molecular classification of breast cancer by quantitative spectroanalysis of horm
Multivariate Survival and Outcome Analysis of 154 Patients with Gastric Cancer at a Single Chinese I
Establishment and identification of a rabbit model of peritoneal carcinomatosis from gastric cancer
PEG-interspersed nitrilotriacetic acid-functionalized quantum dots for site-specific labeling of pri
The quantitative detection of total HER2 load by quantum dots and the identification of a new subtyp
Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of gastric ca
Clathrin-Mediated Endocytosis in Living Host Cells Visualized through Quantum Dot Labeling of Infect
MUC-1 aptamer-conjugated dye-doped silica nanoparticles for MCF-7 cells detection
Kinetics-Controlled Formation of Gold Clusters Using a Quasi-Biological System
Comparative study on the effects of two antifungal drugs against Candida albicans by microcalorimetr
Aptamer Biosensor Based on Fluorescence Resonance Energy Transfer from Upconverting Phosphors to Car
Adjusting the Crystal Phase and Morphology of Titania via a Soft Chemical Process
G-Quadruplex Hinders Translocation of BLM Helicase on DNA: A Real-Time Fluorescence Spectroscopic Un
Simultaneous quantification of amphetamines, caffeine and ketamine in urine by hollow fiber liquid p
Fast and selective magnetic solid phase extraction of trace Cd, Mn and Pb in environmental and biolo
C-18-coated stir bar sorptive extraction combined with high performance liquid chromatography-electr
Porous monoliths: sorbents for miniaturized extraction in biological analysis
吸头小柱微萃取-解吸电晕束电离质谱用于快速分析体液中的降压药物
Synthesis of mixed coating with multi-functional groups for in-tube hollow fiber solid phase microex
Toxicity of CdTe Quantum Dots on Yeast Saccharomyces Cerevisiae
Immunoassays with Protein Misfolding Cycle Amplification: A Platform for Ultrasensitive Detection of
Phase transfer hollow fiber liquid phase microextraction combined with electrothermal vaporizationin
Graphene oxide based fluorescent aptasensor for adenosine deaminase detection using adenosine as the
Stir bar sorptive extraction approaches with a home-made portable electric stirrer for the analysis
Quantum-dots based simultaneous detection of multiple biomarkers of tumor stromal features to predic
Controllable synthesis of PbSe nanocubes in aqueous phase using a quasi-biosystem
Preparation and characterization of rnethacrylate-based monolith for capillary hydrophilic interacti
Spectroscopic and electrochemical studies on the interaction of an inclusion complex of beta-cyclode
Interaction of Human Serum Albumin with Indomethacin: Spectroscopic and Molecular Modeling Studies
Chiral speciation and determination of selenomethionine enantiomers in selenized yeast by ligand-exc
Effectively and Efficiently Dissecting the Infection of Influenza Virus by Quantum-Dot-Based Single-
Electrochemical methods - important means for fabrication of fluorescent nanoparticles
Upconversion Fluorescence Resonance Energy Transfer Based Biosensor for Ultrasensitive Detection of
Real-time luminescence-based colorimetric determination of double-strand DNA in droplet on demand
Sample preparation and direct electrospray ionization on a tip column for rapid mass spectrometry an
Microchip-based immunoassays with application of silicon dioxide nanoparticle film
Facile synthesis and characterization of highly fluorescent and biocompatible N-acetyl-L-cysteine ca
Widespread Existence of Cytosine Methylation in Yeast DNA Measured by Gas Chromatography/Mass Spectr
Systematically investigation of interactions between BSA and different charge-capped CdSe/ZnS quantu
Label-Free Homogeneous Immunosensor Based on FRET for the Detection of Virus Antibody in Serum
Cathepsin B cleavable novel prodrug Ac-Phe-Lys-PABC-ADM enhances efficacy at reduced toxicity in tre
Light-induced pH change and its application to solid phase extraction of trace heavy metals by high-
Determination of glucose and uric acid with bienzyme colorimetry on microfluidic paper-based analysi
Synthesis of Three Novel Anionic Gemini Surfactants and Comparative Studies of Their Assemble Behavi
Droplet-based microscale colorimetric biosensor for multiplexed DNA analysis via a graphenenanoprobe
One-Pot Synthesized DNA-CdTe Quantum Dots Applied in a Biosensor for the Detection of Sequence-Speci
The adsorption of an anticancer hydrazone by protein: an unusual static quenching mechanism
Two-photon Fluorescent Probe for Intracellular Detection of Tyrosinase Activity
Nanometer-sized alumina packed microcolumn solid-phase extraction combined with field-amplified samp
Spectroscopic studies on the interactions between CdTe quantum dots coated with different ligands an
Substrateless graphene fiber: A sorbent for solid-phase microextraction
荧光探针Ru(phen)^2(dppx)^2+测定H1N1禽流感病毒DNA
细胞减灭术加腹腔热灌注化疗治疗结直肠癌腹膜转移癌病例对照研究
胃癌腹膜转移癌治疗研究进展及我国治疗现状
乳斑与腹膜转移癌的相关性研究进展
In Vitro Invasive Pattern of Hepatocellular Carcinoma Cell Line HCCLM9 Based on Three-dimensional Cell Culture and Quantum Dots Molecular Imaging
1MeV电子加速器与辐照加工
水中除硼及其研究
Ki67在乳腺癌的研究进展
巨噬细胞浸润对胃癌进展和预后的影响
The stress response factor RpoS is required for the natural transformation of Escherichia coli
Vascular lumen simulation and highly-sensitive nitric oxide detection using three-dimensional gelati
获奖
以核酸为靶目标的小分子的设计、合成及其生物活性研究
面向临床的中药药性与品质评价模式和方法
以核酸为靶目标的小分子的设计、合成及其生物活性研究
面向临床的中药药性与品质评价模式和方法
庞代文的项目
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会议论文 19
高灵敏快速诊断用荧光-磁性-生物靶向三功能纳米球的研发
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新型生物医学探针技术基础及应用
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多功能纳米生物医学传感探针的研究及其应用
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会议论文 20
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电化学基因传感器的优化
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化学
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微流控系统中的细胞操纵及其系生化组分分化方法研究
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