欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
位置：立项数据库 > 立项详情页
中文摘要：
基于微生物细胞对金属形态的生物萃取原理，在介观流控系统中研究与金属组学相关的形态分析新方法,建立介观流控系统中金属形态的选择性细胞萃取分离富集-原子光谱联用分析系统。包括: 研究细胞在微珠表面的固定化及在阀上实验室中的实时原位表面更新，及介观流控系统中细胞的在线原位培养与固定化；研究混合细胞生物萃取与多形态梯度/顺序洗脱以实现混合形态的色谱型分离；研究通过改变细胞表面功能团种类及数量，以控制细胞萃取的选择性或特异性；探索促进细胞表面的快速被动萃取过程、抑制细胞内部的慢速主动累积/代谢过程的途径，以避免萃取过程中金属形态的转化；研究介观流控系统全血在线微渗析-细胞萃取金属形态阐释集成系统，及介观流控微渗析-微流控电泳芯片金属形态联用分析系统。本项目将为在线评价金属形态对细胞的毒性水平提供依据。
成果综合统计
期刊论文
会议论文
专利
获奖
著作
期刊论文
Sequential injection reductive bio-sorption of Cr(VI) on the surface of egg-shell membrane and chrom
Preconcentration and speciation of chromium in a sequential injection system incorporating dual mini
DNA purification on a lab-on-valve system incorporating a renewable micro-column with in-situ monito
A sequential injection fluorometric procedure for the determination of procaine in human blood and p
Silk fibroin as a sorbent for on line extraction and preconcentration of copper with detection by el
Cell-sorption of paramagnetic metal ions on a cell-immobilized micro-column in the presence of an ex
The extraction of proteins from biological fluids by using an ionic liquid/aqueous dual phase system
Biological cell-sorption for separation/preconcent. of ultra-trace cadmium in a sequential injection
Integrating preconcentration, tetrahydroborate immobilization, elution and chemical vapor generation
Sequential/bead injection lab-on-valve incorporating a renewable microcolumn for co-precipitate prec
Speciation of inorganic arsenic in a sequential injection dual mini-column
system coupled with hydri
Coating of a thin layer of NaBH4 solution for mercury vapor generation coupled to atomic fluorescenc
Bioaccumulation and speciation of arsenic and chromium using biological cells with detection by elec
New developments in flow /sequential injection on-line separation/preconcentration coupled with elec
Field speciation of chromium with a sequential injection lab-on-valve incorporating a bismuthate imm
The development of a miniature atomic fluorescence spectrometric system in a lab-on-valve for mercur
相关项目
王建华的项目