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基于MRI的前庭系统分割与统计形态学分析关键技术研究
  • 项目名称：基于MRI的前庭系统分割与统计形态学分析关键技术研究
  • 项目类别：青年科学基金项目
  • 批准号：81201157
  • 申请代码：H1809
  • 项目来源：国家自然科学基金
  • 研究期限：2013-01-01-2015-12-31
  • 项目负责人：王德峰
  • 依托单位：香港中文大学深圳研究院
  • 批准年度：2012
中文摘要：

前庭系统是人类大脑中的平衡感知器官，许多生理或病理性刺激会引起其内部结构的解剖学变化。由于前庭系统结构复杂，其在形态方面的研究目前仅限于简单的测量与显示，很少有研究能够深入地对其形态展开分析。在青少年特发性脊柱侧弯(AIS)研究中，我们已经对前庭系统中半规管的解剖形态学异常进行了初步分析，但分析方法和精度仍需要极大的改善。因此本项目将致力于探索先进的计算技术实现前庭系统的精确自动分割与定量统计形态学分析，并在此基础上研究其解剖形态学差异与某些疾病(AIS与听力障碍)的相关性。研究以T2加权的磁共振影像为研究对象，在前庭系统统计模型基础上，逐步实现前庭系统的精确分割、高级建模、几何描述、形状分析及统计形态学测量等。该研究将会揭示前庭系统解剖形态学变化或差异与相关疾病之间的关联程度，对相关疾病的预测提供潜在的客观指导，对于内耳病理分析及内耳手术规划等也有极大的帮助。

中文主题词： 前庭系统；青少年特发性脊柱侧弯；图像分割；图像配准；
结论摘要：

英文主题词Vestibular System；AIS；Image Segmentation；Image Registration；

成果综合统计
成果类型
数量
  • 期刊论文
  • 会议论文
  • 专利
  • 获奖
  • 著作
  • 25
  • 28
  • 0
  • 0
  • 0
期刊论文
Altered Topological Organization of Cortical Network in Adolescent Girls with Idiopathic Scoliosis
Application of Multimodal MR Imaging on Studying Alzheimer's Disease: A Survey. Current Alzh
Application of Multimodal MR Imaging on Studying Alzheimer's Disease: A Survey
Excellent side-to-side symmetry in glenoid size and shape
Intensity and Sulci Landmark Combined Brain Atlas Construction for Chinese Pediatric Population
Generation of the Probabilistic Template of Default Mode Network Derived from Resting-State fMRI. IE
Intensity and Sucli Landmark Combined Brain Atlas Construction for Chinese Pediatric Population
Altered default mode network functional connectivity in schizotypal personality disorder
Generation of the Probabilistic Template of Default Mode Network Derived from Resting-State fMRI
Midsagittal plane extraction from brain images based on 3D SIFT
Abnormal Organization of White Matter Network in Patients with no Dementia after Ischemic Stroke
Accelerating Neuroimage Registration through Parallel Computation of Similarity Metric
Predicting Cerebral Hyperperfusion Syndrome Following Superficial Temporal Artery to Middle Cerebral
Adaptive Distance Metric Learning for Diffusion Tensor Image Segmentation
Altered topological organization of brain structural network in Chinese children with developmental
Myocardial Iron Loading Assessment by Automatic Left Ventricle Segmentation with Morphological Opera
Histogram-based Normalization Technique on Human Brain Magnetic Resonance Images from Different Acqu
Volumetric Changes in Cerebella Regions in Adolescent Idiopathic Scoliosis as Compared with Healthy
Variation in Anisotropy and Diffusivity Along Medulla Oblongata and the Whole Spinal Cord in Adolesc
会议论文
The Application of Delayed-Enhancement MRI on Atrial Fibrillation Ablation
Morphometric Changes of Semicircular Canals in Adolescent Idiopathic Scoliosis
An Intelligent Pipeline for Designing Personalized Orthopedic Casts
Computer-assisted Surgical Planning for BoneBridge Implantation
Dynamic contrast-enhanced low-field (0.25T) MRI wrist in rheumatoid arthritis compared with high-fie
Template Building For Chinese Children And Adolescent And Comparison With Western Standard Template
A Theoretical Based Computer Exercise to Measure and Enhance Attention and Inhibition Performance in
Altered Topological Organization of Brain Structural Network in Chinese Children with Developmental
A GPU Implementation of Fast Non-rigid Image Registration Method Based on Advanced Normalization Too
Real-time Left Ventricular Speckle-Tracking in 3D Echocardiography with Parallel Block Matching
Robust Automated Assessment of Myocardial Iron Loading
Statistical Morphometry of Vestibular System in Adolescent Idiopathic Scoliosis
Statistical Analysis of Brainstem Morphology using Differential Geometry in Patients with Adolescent
Statistical Morphometry of the Vestibular System in Adolescent Idiopathic Scoliosis
Changed Canal length of Vestibular System in Adolescent Idiopathic Scoliosis. in Proc.
Statistical Morphometry of Vestibular System in Adolescent Idiopathic Scoliosis.
Quantitative Analysis of Structural Abnormality of the Vestibular System in Progressive and Non-Prog
Low Dose X-ray Image Restoration via SAE Neural Network
Altered Cortical Network in Female with Adolescent Idiopathic Scoliosis
Dynamic Fast Breath-hold MRI Based Pre- and Post-spinal Fusion Lung Volume Analysis in Patients with
Automated Segmentation of Vertebral Body in Magnetic Resonance Images – A Hybrid Model
Hybrid Modelling Based Automatic Algorithm for Vertebral Body Segmentation in Magnetic Resonance Ima
An Automatic Method for Vertebra Body Segmentation in Magnetic Resonance Images based on Hybrid Mode
An Automatic Method for Stitching of Spinal Diffusion Tensor Images
GPU Accelerated CBCT Reconstruction from Few Views with SART and TV Regularization
Statistical Analysis of Cerebellum Sub-regional Volumes in Patients with Adolescent Idiopathic Scol
Length Alteration of the Semicircular Canal in Patients with Adolescent Idiopathic Scoliosis
GPU Accelerated Flirt Algorithm for Neuroimage Registration
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