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金属抗肿瘤药物相互作用组学的方法学研究
  • 项目名称：金属抗肿瘤药物相互作用组学的方法学研究
  • 项目类别：国际(地区)合作与交流项目
  • 批准号：21020102039
  • 项目来源：国家自然科学基金
  • 研究期限：1900-01-01-1900-01-01
  • 项目负责人：汪福意
  • 依托单位：中国科学院化学研究所
  • 批准年度：2010
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  • 期刊论文
  • 会议论文
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期刊论文
Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1
Transferrin Serves As a Mediator to Deliver Organometallic Ruthenium(II) Anticancer Complexes into C
Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazoli
The anticancer drug cisplatin can cross-link the interdomain zinc site on human albumin
A comparative study on interactions of cisplatin and ruthenium arene anticancer complexes with metal
Competition between glutathione and DNA oligonucleotides for ruthenium(II) arene anticancer complexe
Thymines in Single-Stranded Oligonucleotides and G-Quadruplex DNA Are Competitive with Guanines for
Competitive Binding Sites of a Ruthenium Arene Anticancer Complex on Oligonucleotides Studied by Mas
Mechanism of interstrand migration of organoruthenium anticancer complexes within a DNA duplex
De Novo Generation of Singlet Oxygen and Ammine Ligands by Photoactivation of a Platinum Anticancer
Organometallic ruthenium anticancer complexes inhibit human glutathione-S-transferase pi
Elucidation of the binding sites of sodium dodecyl sulfate to beta-lactoglobulin using hydrogen/deut
会议论文
Organometallic Ruthenium Complexes Exhibit Inhibition on PTP1B via Dual Attacking at Active Thiols
Identification of Binding Sites of Organoruthenium Anticancer Complexes to DNA by Mass Spectrometry:
Identification of binding sites of a Ruthenium anticancer complex on oligonucleotides by mass spectr
Investigation on Interactions of Metal-based Anticancer Agents with Serum Proteins by Mass Spectrome
Combined Application of LC-ESI-MS and ICP-MS for Investigation on Interactions of Metal-based Antica
汪福意的项目
基于信号转导过程的组合分子抗癌药物设计和作用机理研究
期刊论文 6 会议论文 8
液质联用和多维核磁光谱研究综合分子金属抗癌药物与靶分子的相互作用
基于化学遗传学的金属抗肿瘤药物分子作用机理研究新方法
期刊论文 1
调控蛋白与药物损伤DNA相互作用研究的分析新方法
期刊论文 2
LC－MS研究有机金属钌抗肿瘤化合物与血清蛋白的相互作用
期刊论文 16 会议论文 20